| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4841342 | B | Inhibition of RSK4 (unknown origin) incubated for 40 mins in presence of ATP and lipid substrate by Kinase-Glo plus luminescence assay | Homo sapiens | 24 | ALA4840336 | single protein format | Scientific Literature | |
| 2. | ALA4841343 | B | Inhibition of RSK4 in human TE-10 cells assessed as suppression of RPS6 phosphorylation measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4840336 | cell-based format | Scientific Literature | |
| 3. | ALA4841344 | B | Inhibition of RSK4 in human TE-10 cells assessed as suppression of GSK3beta phosphorylation measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4840336 | cell-based format | Scientific Literature | |
| 4. | ALA4841345 | B | Inhibition of RSK4 in human TE-10 cells assessed as suppression of RPS6 phosphorylation at 10 uM measured after 24 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA4840336 | cell-based format | Scientific Literature | |
| 5. | ALA4841346 | B | Inhibition of RSK4 in human TE-10 cells assessed as suppression of GSK3beta phosphorylation at 10 uM measured after 24 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA4840336 | cell-based format | Scientific Literature | |
| 6. | ALA4841347 | B | Inhibition of RSK1 in human TE-10 cells assessed as suppression of EIF4B phosphorylation at 1 to 10 uM measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4840336 | cell-based format | Scientific Literature | |
| 7. | ALA4841348 | B | Inhibition of RSK1 in human TE-10 cells assessed as suppression of P27KIP1 phosphorylation at 1 to 10 uM measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4840336 | cell-based format | Scientific Literature | |
| 8. | ALA4841349 | B | Inhibition of RSK2 in human TE-10 cells assessed as suppression of creb-phosphorylation at 1 to 10 uM measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4840336 | cell-based format | Scientific Literature | |
| 9. | ALA4841350 | B | Inhibition of RSK2 in human TE-10 cells assessed as suppression of HSP27 at residue 32 phosphorylation at 1 to 10 uM measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4840336 | cell-based format | Scientific Literature | |
| 10. | ALA4841351 | B | Inhibition of RSK2 in human TE-10 cells assessed as suppression of HSP27 at residue 33 phosphorylation at 1 to 10 uM measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4840336 | cell-based format | Scientific Literature | |
| 11. | ALA4841352 | B | Inhibition of RSK3 in human TE-10 cells assessed as suppression of c-fos phosphorylation at 1 to 10 uM measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4840336 | cell-based format | Scientific Literature | |
| 12. | ALA4841353 | B | Inhibition of RSK3 in human TE-10 cells assessed as suppression of HistoneH3 phosphorylation at residue 34 at 1 to 10 uM measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4840336 | cell-based format | Scientific Literature | |
| 13. | ALA4841354 | B | Inhibition of RSK3 in human TE-10 cells assessed as suppression of HistoneH3 phosphorylation at residue 35 at 1 to 10 uM measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4840336 | cell-based format | Scientific Literature | |
| 14. | ALA4841355 | B | Inhibition of RSK1 (unknown origin) at 100 nM relative to control | Homo sapiens | 1 | ALA4840336 | single protein format | Scientific Literature | |
| 15. | ALA4841356 | B | Inhibition of RSK2 (unknown origin) at 100 nM relative to control | Homo sapiens | 1 | ALA4840336 | single protein format | Scientific Literature | |
| 16. | ALA4841357 | B | Inhibition of RSK3 (unknown origin) at 100 nM relative to control | Homo sapiens | 1 | ALA4840336 | single protein format | Scientific Literature | |
| 17. | ALA4841358 | F | Inhibition of cell invasion in human TE-10 cells measured after 24 hrs by Giemsa staining based transwell invasion assay | Homo sapiens | 2 | ALA4840336 | cell-based format | Scientific Literature | |
| 18. | ALA4841359 | F | Potency index, ratio of BI-D1870 IC50 to test compound IC50 for inhibition of cell invasion in human TE-10 cells measured after 24 hrs by Giemsa staining based transwell invasion assay | Homo sapiens | 1 | ALA4840336 | cell-based format | Scientific Literature | |
| 19. | ALA4841360 | F | Antiproliferative activity against human TE-10 cells assessed as inhibition of cell proliferation measured up to 48 hrs by CCK-8 assay | Homo sapiens | 2 | ALA4840336 | cell-based format | Scientific Literature | |
| 20. | ALA4841361 | F | Potency index, ratio of BI-D1870 IC50 to test compound IC50 for antiproliferative activity against human TE-10 cells assessed as inhibition of cell proliferation measured up to 48 hrs by CCK-8 assay | Homo sapiens | 1 | ALA4840336 | cell-based format | Scientific Literature |
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