# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4818953 | Functional | Antibacterial activity against Clostridium difficile ATCC 43255 assessed as reduction in bacterial growth measured after 48 hrs by CLSI based broth microdilution method | Clostridioides difficile | 28 | ALA4814079 | organism-based format | Scientific Literature | |
2. | ALA4818954 | Functional | Antibacterial activity against methicilin-resistant Staphylococcus aureus ATCC 29213 assessed as reduction in bacterial growth measured after 48 hrs by CLSI based broth microdilution method | Staphylococcus aureus | 25 | ALA4814079 | organism-based format | Scientific Literature | |
3. | ALA4818964 | Functional | Selectivity index, ratio of MIC of methicillin-resistant Staphylococcus aureus ATCC 29213 to MIC of Clostridium difficile ATCC 43255 | 24 | ALA4814079 | assay format | Scientific Literature | ||
4. | ALA4818967 | ADME | Cytotoxicity against human HeLa cells assessed as reduction in cell viability at 128 ug/ml incubated for 16 hrs by XTT assay | Homo sapiens | 1 | ALA4814079 | cell-based format | Scientific Literature | |
5. | ALA4818968 | ADME | Drug excretion in CD1 mouse feces at 20 mg/kg, po measured upto 8 hrs by LC-MS/MS analysis | Mus musculus | 5 | ALA4814079 | organism-based format | Scientific Literature | |
6. | ALA4818970 | ADME | Plasma concentration in CD1 mouse at 20 mg/kg, po measured upto 8 hrs by LC-MS/MS analysis | Mus musculus | 5 | ALA4814079 | organism-based format | Scientific Literature | |
7. | ALA4818972 | Toxicity | Ratio of drug excretion in CD-1 mouse feces to MIC for antibacterial activity against Clostridium difficile ATCC 43255 | 6 | ALA4814079 | assay format | Scientific Literature |