# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4836936 | Binding | Inhibition of BCL-XL(unknown origin) at 10 uM incubated for 120 mins by TR-FRET assay relative to control | Homo sapiens | 4 | ALA4834480 | single protein format | Scientific Literature | |
2. | ALA4836940 | Binding | Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 30 mins fluorescence polarization-based competitive binding assay | Homo sapiens | 49 | ALA4834480 | assay format | Scientific Literature | |
3. | ALA4836944 | Binding | Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged BCL2 (1 to 205 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) at 10 uM incubated for 30 mins fluorescence polarization-based competitive binding assay relative to control | Homo sapiens | 5 | ALA4834480 | assay format | Scientific Literature | |
4. | ALA4836945 | Binding | Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged BFL1 (1 to 151 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) at 10 uM incubated for 30 mins fluorescence polarization-based competitive binding assay relative to control | Homo sapiens | 4 | ALA4834480 | assay format | Scientific Literature | |
5. | ALA4836950 | Functional | Antiproliferative activity against human NCI-H929 cells assessed as decrease in cell viability measured after 72 hrs by MTT assay | Homo sapiens | 8 | ALA4834480 | cell-based format | Scientific Literature | |
6. | ALA4836951 | Functional | Antiproliferative activity against human MV4-11 cells assessed as decrease in cell viability measured after 72 hrs by MTT assay | Homo sapiens | 8 | ALA4834480 | cell-based format | Scientific Literature | |
7. | ALA4836952 | Functional | Antiproliferative activity against human SK-BR-3 cells assessed as decrease in cell viability measured after 72 hrs by MTT assay | Homo sapiens | 8 | ALA4834480 | cell-based format | Scientific Literature | |
8. | ALA4836953 | Functional | Antiproliferative activity against human NCI-H23 cells assessed as decrease in cell viability measured after 72 hrs by MTT assay | Homo sapiens | 8 | ALA4834480 | cell-based format | Scientific Literature | |
9. | ALA4836954 | Functional | Antiproliferative activity against human K562 cells assessed as decrease in cell viability measured after 72 hrs by MTT assay | Homo sapiens | 8 | ALA4834480 | cell-based format | Scientific Literature |