# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4812655 | B | Inhibition of Plasmodium falciparum DHODH expressed in Escherichia coli BL21-DE3 using L-dihydroorotate as substrate by steady-state DCIP method | Plasmodium falciparum | 107 | assay format | Scientific Literature | ||
2. | ALA4812656 | B | Inhibition of Plasmodium vivax DHODH expressed in Escherichia coli BL21-DE3 using L-dihydroorotate as substrate by steady-state DCIP method | Plasmodium vivax | 65 | assay format | Scientific Literature | ||
3. | ALA4812657 | A | Inhibition of human DHODH expressed in Escherichia coli BL21-DE3 using L-dihydroorotate as substrate by steady-state DCIP method | Homo sapiens | 67 | assay format | Scientific Literature | ||
4. | ALA4812658 | F | Antimalarial activity against drug-resistant Plasmodium falciparum 3D7 infected in human erythrocytes assessed as reduction in parasite growth measured after 72 hrs by SYBR Green method | Plasmodium falciparum | 107 | organism-based format | Scientific Literature | ||
5. | ALA4812661 | A | Inhibition of rat DHODH up to 100 uM | Rattus norvegicus | 5 | single protein format | Scientific Literature | ||
6. | ALA4812662 | A | Inhibition of human DHODH up to 100 uM | Homo sapiens | 5 | single protein format | Scientific Literature | ||
7. | ALA4812663 | A | Inhibition of mouse DHODH up to 100 uM | Mus musculus | 5 | single protein format | Scientific Literature | ||
8. | ALA4812664 | A | Inhibition of dog DHODH up to 100 uM | Canis lupus familiaris | 5 | assay format | Scientific Literature | ||
9. | ALA4812665 | A | Cytotoxicity against mouse L1210 cells | Mus musculus | 5 | cell-based format | Scientific Literature | ||
10. | ALA4812666 | A | Cytotoxicity against human HepG2 cells | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
11. | ALA4812667 | B | Inhibition of human ERG by QPatch assay | Homo sapiens | 5 | single protein format | Scientific Literature | ||
12. | ALA4812668 | T | Mutagenicity in Salmonella typhimurium by Ames test | Salmonella enterica subsp. enterica serovar Typhimurium | 2 | assay format | Scientific Literature | ||
13. | ALA4812670 | A | Inhibition of CYP1A2 (unknown origin) using phenacetin O-deethylation by UPLC-MS analysis | Homo sapiens | 5 | single protein format | Scientific Literature | ||
14. | ALA4812671 | A | Inhibition of CYP2B6 (unknown origin) by UPLC-MS analysis | Homo sapiens | 5 | single protein format | Scientific Literature | ||
15. | ALA4812672 | A | Inhibition of CYP2C8 (unknown origin) by UPLC-MS analysis | Homo sapiens | 5 | single protein format | Scientific Literature | ||
16. | ALA4812673 | A | Inhibition of CYP2C9 (unknown origin) by UPLC-MS analysis | Homo sapiens | 5 | single protein format | Scientific Literature | ||
17. | ALA4812674 | A | Inhibition of CYP2C19 (unknown origin) by UPLC-MS analysis | Homo sapiens | 5 | single protein format | Scientific Literature | ||
18. | ALA4812675 | A | Inhibition of CYP2D6 (unknown origin) by UPLC-MS analysis | Homo sapiens | 5 | single protein format | Scientific Literature | ||
19. | ALA4812676 | A | Time dependent inhibition of CYP3A4 (unknown origin) | Homo sapiens | 5 | single protein format | Scientific Literature | ||
20. | ALA4812677 | A | Inhibition of CYP3A4 (unknown origin) by UPLC-MS analysis | Homo sapiens | 5 | single protein format | Scientific Literature |