| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4839263 | B | Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay | Homo sapiens | 22 | single protein format | Scientific Literature | ||
| 2. | ALA4839264 | B | Potency index, ratio of IC50 for LRE1 to IC50 for test compound for inhibition of human soluble adenylyl cyclase | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 3. | ALA4839265 | B | Inhibition of human soluble adenylyl cyclase transfected (4-4 clones)in human HEK293 cells assessed as reduction in cAMP levels preincubated for 5 mins with test compounds in the presence of IBMX by ELISA | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 4. | ALA4839266 | A | Permeability of the compound in PRISMA HT buffer at pH 7.4 at 10 umol/L incubated for 3 hrs bt PAMPA based LC/MS/MS analysis | 4 | assay format | Scientific Literature | |||
| 5. | ALA4839267 | P | Octanol-water partition coefficient, logD of the compound at pH 7.4 by HPLC analysis | 4 | small-molecule physicochemical format | Scientific Literature | |||
| 6. | ALA4839268 | P | Kinetic solubility of compound by UV- absorbance analysis | 4 | small-molecule physicochemical format | Scientific Literature |
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