| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4836402 | B | Inhibition of human liver mitochondrial KMO assessed as reduction in 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins followed by substate addition and measured after 30 mins by LC-MS/MS analysis | Homo sapiens | 17 | mitochondrion format | Scientific Literature | ||
| 2. | ALA4836403 | A | Metabolic stability in human liver microsomes assessed as intrinsic clearance incubated for 30 mins in presence of NADPH measured per mg protein | Homo sapiens | 17 | microsome format | Scientific Literature | ||
| 3. | ALA4836404 | A | Metabolic stability in rat liver microsomes assessed as intrinsic clearance incubated for 30 mins in presence of NADPH measured per mg protein | Rattus norvegicus | 17 | microsome format | Scientific Literature | ||
| 4. | ALA4836405 | P | Glutathione reactivity assessed as dansylatedGSH-compound conjugate formation in presence of human liver microsomes by fluorescence detector based HPLC analysis | 17 | microsome format | Scientific Literature | |||
| 5. | ALA4836406 | A | Plasma concentration in mouse at 2 mg/kg, po | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 6. | ALA4836408 | A | Ratio of drug concentration in brain to plasma in mouse at 2 mg/kg, po | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 7. | ALA4836420 | A | Drug concentration in mouse brain at 2 mg/kg, po measured per gm of tissue | Mus musculus | 3 | organism-based format | Scientific Literature |
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