| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4844594 | B | Protac activity at CRBN/AR in human VCaP cells assessed as AR degradation after 24 hrs by Western blot analysis | Homo sapiens | 40 | cell-based format | Scientific Literature | ||
| 2. | ALA4844595 | B | Protac activity at CRBN/AR in human VCaP cells assessed as maximal AR degradation after 24 hrs by Western blot analysis relative to control | Homo sapiens | 40 | cell-based format | Scientific Literature | ||
| 3. | ALA4844596 | A | Half life in SCID mouse at 1 mg/kg, iv by LC-MS/MS analysis | Mus musculus | 7 | organism-based format | Scientific Literature | ||
| 4. | ALA4844597 | A | AUC (0 to t) in SCID mouse at 1 mg/kg, iv by LC-MS/MS analysis | Mus musculus | 7 | organism-based format | Scientific Literature | ||
| 5. | ALA4844598 | A | Volume of distribution at steady state in SCID mouse at 1 mg/kg, iv by LC-MS/MS analysis | Mus musculus | 7 | organism-based format | Scientific Literature | ||
| 6. | ALA4844602 | A | Tmax in SCID mouse at 3 mg/kg, po by LC-MS/MS analysis | Mus musculus | 7 | organism-based format | Scientific Literature | ||
| 7. | ALA4844603 | A | Half life in SCID mouse at 3 mg/kg, po by LC-MS/MS analysis | Mus musculus | 7 | organism-based format | Scientific Literature | ||
| 8. | ALA4844604 | A | Cmax in SCID mouse at 3 mg/kg, po by LC-MS/MS analysis | Mus musculus | 7 | organism-based format | Scientific Literature | ||
| 9. | ALA4844605 | A | AUC (0 to t) in SCID mouse at 3 mg/kg, po by LC-MS/MS analysis | Mus musculus | 7 | organism-based format | Scientific Literature | ||
| 10. | ALA4844606 | A | Oral bioavailability in SCID mouse at 3 mg/kg by LC-MS/MS analysis | Mus musculus | 7 | organism-based format | Scientific Literature | ||
| 11. | ALA4844612 | F | Growth inhibition of human VCaP cells assessed as cell viability by WST-8 assay | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
| 12. | ALA4844613 | B | Protac activity at CRBN/AR T878A mutant in human LNCaP cells assessed as AR degradation after 24 hrs by Western blot analysis | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 13. | ALA4844614 | B | Protac activity at CRBN/AR T878A mutant in human LNCaP cells assessed as maximal AR degradation after 24 hrs by Western blot analysis relative to control | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 14. | ALA4844615 | F | Growth inhibition of human LNCaP cells carrying AR T878A mutant assessed as cell viability by WST-8 assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 15. | ALA4844616 | B | Protac activity at CRBN/AR in human VCaP cells assessed as reduction in AR protein level after 6 hrs by Western blot analysis relative to control | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 16. | ALA4844617 | B | Protac activity at CRBN/AR T878A mutant in human LNCaP cells assessed as reduction in AR protein level after 6 hrs by Western blot analysis relative to control | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 17. | ALA4844618 | B | Protac activity at CRBN/AR in human VCaP cells assessed as reduction in AR protein level after 24 hrs by Western blot analysis relative to control | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 18. | ALA4844619 | B | Protac activity at CRBN/AR T878A mutant in human LNCaP cells assessed as reduction in AR protein level after 24 hrs by Western blot analysis relative to control | Homo sapiens | 9 | cell-based format | Scientific Literature |
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