# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4817528 | B | Inhibition of ASM in dog MDCK cells co-expressing recombinant full length mGFP-tagged KRAS G12V mutant and mCherry-CAAX assessed as reduction in plasma membrane localization of KRAS mutant incubated for 48 hrs by confocal microscopic analysis | Canis lupus familiaris | 29 | cell membrane format | Scientific Literature | ||
2. | ALA4817529 | B | Inhibition of ASM in dog MDCK cells co-expressing recombinant full length mGFP-tagged KRAS G12V mutant and mCherry-CAAX assessed as reduction in plasma membrane localization of KRAS mutant incubated for 48 hrs by confocal microscopic analysis relative to control | Canis lupus familiaris | 29 | cell membrane format | Scientific Literature | ||
3. | ALA4817530 | F | Cytotoxicity against dog MDCK cells at 30 uM | Canis lupus familiaris | 29 | cell-based format | Scientific Literature | ||
4. | ALA4817536 | F | Antiproliferative activity against human BXPC-3 cells expressing wild type KRAS assessed as reduction in cell growth incubated for 72 hrs by CyQuant proliferation assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
5. | ALA4817537 | F | Antiproliferative activity against human MIA PaCa-2 cells expressing KRAS mutant assessed as reduction in cell growth incubated for 72 hrs by CyQuant proliferation assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
6. | ALA4817538 | F | Antiproliferative activity against human MOH cells expressing KRAS mutant assessed as reduction in cell growth incubated for 72 hrs by CyQuant proliferation assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
7. | ALA4817539 | F | Antiproliferative activity against human MPANC96 cells expressing KRAS mutant assessed as reduction in cell growth incubated for 72 hrs by CyQuant proliferation assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
8. | ALA4817540 | F | Antiproliferative activity against human Ishikawa cells expressing wild type KRAS assessed as reduction in cell growth incubated for 72 hrs by CyQuant proliferation assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
9. | ALA4817541 | F | Antiproliferative activity against human HEC-1-A cells expressing mutant KRAS assessed as reduction in cell growth incubated for 72 hrs by CyQuant proliferation assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
10. | ALA4817542 | F | Antiproliferative activity against human HEC-1B cells expressing mutant KRAS assessed as reduction in cell growth incubated for 72 hrs by CyQuant proliferation assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
11. | ALA4817543 | F | Antiproliferative activity against human Caco-2 cells expressing wild type KRAS assessed as reduction in cell growth incubated for 72 hrs by CyQuant proliferation assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
12. | ALA4817544 | F | Antiproliferative activity against human SK-CO-1 cells expressing mutant KRAS assessed as reduction in cell growth incubated for 72 hrs by CyQuant proliferation assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
13. | ALA4817545 | F | Antiproliferative activity against human NCI-H1975 cells expressing wild type KRAS assessed as reduction in cell growth incubated for 72 hrs by CyQuant proliferation assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
14. | ALA4817546 | F | Antiproliferative activity against human NCI-H522 cells expressing wild type KRAS assessed as reduction in cell growth incubated for 72 hrs by CyQuant proliferation assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
15. | ALA4817547 | F | Antiproliferative activity against human NCI-H1299 cells expressing wild type KRAS assessed as reduction in cell growth incubated for 72 hrs by CyQuant proliferation assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
16. | ALA4817548 | F | Antiproliferative activity against human NCI-H23 cells expressing mutant KRAS assessed as reduction in cell growth incubated for 72 hrs by CyQuant proliferation assay | Homo sapiens | 5 | cell-based format | Scientific Literature |