# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4807083 | F | Antagonist activity at Wnt3a-stimulated frizzled-2 (unknown origin) expressed in human HEK293superTOP flash cells incubated for 24 hrs by luciferase reporter gene assay | Homo sapiens | 8 | ALA4806959 | cell-based format | Patent Bioactivity Data | |
2. | ALA4807084 | F | Antagonist activity at frizzled-2 (unknown origin) expressed in human HEK293superTOP flash cells incubated for 24 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA4806959 | cell-based format | Patent Bioactivity Data | |
3. | ALA4807085 | F | Antagonist activity at Wnt3a-stimulated frizzled-1 (unknown origin) expressed in human HEK293superTOP flash cells incubated for 24 hrs by luciferase reporter gene assay | Homo sapiens | 8 | ALA4806959 | cell-based format | Patent Bioactivity Data | |
4. | ALA4807090 | F | Antagonist activity at Wnt3a-stimulaed frizzled-4 (unknown origin) expressed in human HEK293superTOP flash cells incubated for 24 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA4806959 | cell-based format | Patent Bioactivity Data | |
5. | ALA4807091 | F | Antagonist activity at Wnt3a-stimulaed frizzled-5 (unknown origin) expressed in human HEK293superTOP flash cells incubated for 24 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA4806959 | cell-based format | Patent Bioactivity Data | |
6. | ALA4807092 | F | Antagonist activity at frizzled-1 (unknown origin) expressed in rat C-FIT cells assessed as inhibition of Wnt3a-stimulated blockade of migration at 10 nM incubated for 48 hrs and measured for 24 hrs following the scratch by scratch wound healing assay | Homo sapiens | 1 | ALA4806959 | cell-based format | Patent Bioactivity Data | |
7. | ALA4807093 | F | Antagonist activity at frizzled-2 (unknown origin) expressed in rat C-FIT cells assessed as inhibition of Wnt3a-stimulated blockade of migration at 10 nM incubated for 48 hrs and measured for 24 hrs following the scratch by scratch wound healing assay | Homo sapiens | 1 | ALA4806959 | cell-based format | Patent Bioactivity Data | |
8. | ALA4807094 | B | Antagonist activity at rat frizzled-1 expressed in rat C-FIT cells assessed as inhibition of Wnt3a-stimulated blockade of migration at 10 nM incubated for 48 hrs and measured for 24 hrs following the scratch by scratch wound healing assay | Rattus norvegicus | 1 | ALA4806959 | cell-based format | Patent Bioactivity Data | |
9. | ALA4807095 | B | Antagonist activity at rat frizzled-1 expressed in rat C-FIT cells assessed as inhibition of Wnt5a-stimulated blockade of migration at 10 nM incubated for 48 hrs and measured for 24 hrs following the scratch by scratch wound healing assay | Rattus norvegicus | 1 | ALA4806959 | cell-based format | Patent Bioactivity Data | |
10. | ALA4807096 | B | Antagonist activity at rat frizzled-2 expressed in rat C-FIT cells assessed as inhibition of Wnt3a-stimulated blockade of migration at 10 nM incubated for 48 hrs and measured for 24 hrs following the scratch by scratch wound healing assay | Rattus norvegicus | 1 | ALA4806959 | cell-based format | Patent Bioactivity Data | |
11. | ALA4807097 | B | Antagonist activity at rat frizzled-2 expressed in rat C-FIT cells assessed as inhibition of Wnt5a-stimulated blockade of migration at 10 nM incubated for 48 hrs and measured for 24 hrs following the scratch by scratch wound healing assay | Rattus norvegicus | 1 | ALA4806959 | cell-based format | Patent Bioactivity Data | |
12. | ALA4807098 | F | Antagonist activity at frizzled-1 (unknown origin) expressed in rat C-FIT cells assessed as inhibition of Wnt3a-stimulated cell differentiation changes by measuring alpha-smooth muscle actin gene expression at 10 nM by quantitative RT-PCR analysis | Homo sapiens | 1 | ALA4806959 | cell-based format | Patent Bioactivity Data | |
13. | ALA4807099 | F | Antagonist activity at frizzled-1 (unknown origin) expressed in rat C-FIT cells assessed as inhibition of Wnt5a-stimulated cell differentiation changes by measuring alpha-smooth muscle actin gene expression at 10 nM by quantitative RT-PCR analysis | Homo sapiens | 1 | ALA4806959 | cell-based format | Patent Bioactivity Data | |
14. | ALA4807100 | F | Antagonist activity at frizzled-2 (unknown origin) expressed in rat C-FIT cells assessed as inhibition of Wnt3a-stimulated cell differentiation changes by measuring alpha-smooth muscle actin gene expression at 10 nM by quantitative RT-PCR analysis | Homo sapiens | 1 | ALA4806959 | cell-based format | Patent Bioactivity Data | |
15. | ALA4807101 | F | Antagonist activity at frizzled-2 (unknown origin) expressed in rat C-FIT cells assessed as inhibition of Wnt5a-stimulated cell differentiation changes by measuring alpha-smooth muscle actin gene expression at 10 nM by quantitative RT-PCR analysis | Homo sapiens | 1 | ALA4806959 | cell-based format | Patent Bioactivity Data | |
16. | ALA4807102 | A | Half life in Swiss mouse at 15 ng, iv by HPLC analysis | Mus musculus | 1 | ALA4806959 | organism-based format | Patent Bioactivity Data | |
17. | ALA4807103 | A | Half life in rat | Rattus norvegicus | 1 | ALA4806959 | assay format | Patent Bioactivity Data | |
18. | ALA4807104 | B | Agonist activity at rat frizzled-1 expressed in human HEK293superTOP flash cells by luciferase reporter gene assay | Rattus norvegicus | 3 | ALA4806959 | cell-based format | Patent Bioactivity Data | |
19. | ALA4807105 | B | Agonist activity at rat frizzled-2 expressed in human HEK293superTOP flash cells by luciferase reporter gene assay | Rattus norvegicus | 3 | ALA4806959 | cell-based format | Patent Bioactivity Data | |
20. | ALA4807106 | B | Antagonist activity at Wnt3a-stimulated rat frizzled-1 expressed in human HEK293superTOP flash cells at 10 nM incubated for 24 hrs by luciferase reporter gene assay relative to control | Rattus norvegicus | 3 | ALA4806959 | cell-based format | Patent Bioactivity Data |