| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4807528 | B | Inhibition of BODIPY-FL-labeled AT-7519 binding to human His-tagged CDK12/CycK assessed as BODIPY-FL-labeled AT-7519 binding by measuring fluorescence intensity at 1 uM incubated for 120 mins in presence of 30 uM BODIPY-FL-labeled AT-7519 by TR-FRET assay relative to control | Homo sapiens | 38 | protein complex format | Patent Bioactivity Data | ||
| 2. | ALA4807531 | F | Antiproliferative activity against human A2780 cells at 1 uM by CellTiter-Glo reagent assay relative to control | Homo sapiens | 49 | cell-based format | Patent Bioactivity Data | ||
| 3. | ALA4807532 | F | Anticancer activity against human SUM149PT cells subcutaneously transplanted in abdomen of BALB/cAJcl-nu/nu mouse assessed as tumor volume at 60 mg/kg, po twice a day for 2 weeks measured after 14 days relative to control | Homo sapiens | 1 | organism-based format | Patent Bioactivity Data |
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