# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4839491 | F | Antiallergic activity against anti-DNP-IgE sensitized rat RBL-2H3 cells assessed as induction of degranulation by measuring beta-hexosaminidase release using P-nitrophenyl-N-acetyl-D-glucosamide as substrate measured after 1 hr by microplate reader | Rattus norvegicus | 20 | cell-based format | Scientific Literature | ||
2. | ALA4839492 | A | Cytotoxicity against rat RBL2H3 cells assessed as cell viability incubated for 24 hrs by CCK-8 assay | Rattus norvegicus | 13 | cell-based format | Scientific Literature | ||
3. | ALA4839493 | T | Therapeutic index, ratio of CC50 for rat RBL2H3 cells to IC50 for Antiallergic activity against anti-DNP-IgE sensitized rat RBL-2H3 cells | 13 | assay format | Scientific Literature | |||
4. | ALA4839494 | B | Inhibition of human recombinant CSF1R using ATP/Ulight-TK peptide incubated for 15 mins | Homo sapiens | 13 | single protein format | Scientific Literature | ||
5. | ALA4839495 | F | Antiallergic activity against anti-DNP-IgE sensitized rat RBL-2H3 cells assessed as induction of degranulation by measuring beta-hexosaminidase release using P-nitrophenyl-N-acetyl-D-glucosamide as substrate at 1 uM measured after 1 hr by microplate reader relative to control | Rattus norvegicus | 36 | cell-based format | Scientific Literature | ||
6. | ALA4839496 | F | Antiallergic activity against anti-DNP-IgE sensitized rat RBL-2H3 cells assessed as induction of degranulation by measuring beta-hexosaminidase release using P-nitrophenyl-N-acetyl-D-glucosamide as substrate at 0.2 uM measured after 1 hr by microplate reader relative to control | Rattus norvegicus | 36 | cell-based format | Scientific Literature | ||
7. | ALA4839497 | F | Antiallergic activity against anti-DNP-IgE sensitized rat RBL-2H3 cells assessed as induction of degranulation by measuring beta-hexosaminidase release using P-nitrophenyl-N-acetyl-D-glucosamide as substrate at 0.04 uM measured after 1 hr by microplate reader relative to control | Rattus norvegicus | 36 | cell-based format | Scientific Literature | ||
8. | ALA4839525 | B | Inhibition of human recombinant ABL1 using ATP/Ulight-TK peptide at 5 nM incubated for 15 mins relative to control | Homo sapiens | 3 | single protein format | Scientific Literature | ||
9. | ALA4839526 | B | Inhibition of human full length recombinant BLK at 5 nM by radiometric scintillation counting analysis relative to control | Homo sapiens | 3 | single protein format | Scientific Literature | ||
10. | ALA4839527 | B | Inhibition of human full length recombinant Bmx at 5 nM by radiometric scintillation counting analysis relative to control | Homo sapiens | 3 | single protein format | Scientific Literature | ||
11. | ALA4839528 | B | Inhibition of human recombinant BRK (174 to 734) at 5 nM by radiometric scintillation counting analysis relative to control | Homo sapiens | 3 | single protein format | Scientific Literature | ||
12. | ALA4839529 | B | Inhibition of human full length recombinant BTK at 5 nM by radiometric scintillation counting analysis relative to control | Homo sapiens | 3 | single protein format | Scientific Literature | ||
13. | ALA4839530 | B | Inhibition of human recombinant c-Kit at 5 nM by radiometric scintillation counting analysis relative to control | Homo sapiens | 3 | single protein format | Scientific Literature | ||
14. | ALA4839531 | B | Inhibition of human full length recombinant CSK at 5 nM by radiometric scintillation counting analysis relative to control | Homo sapiens | 3 | single protein format | Scientific Literature | ||
15. | ALA4839532 | B | Inhibition of human recombinant FGR (456 to 770) at 5 nM by radiometric scintillation counting analysis relative to control | Homo sapiens | 3 | single protein format | Scientific Literature | ||
16. | ALA4839533 | B | Inhibition of human recombinant CSF1R using ATP/Ulight-TK peptide at 5 nM incubated for 15 mins relative to control | Homo sapiens | 3 | single protein format | Scientific Literature | ||
17. | ALA4839534 | B | Inhibition of human recombinant Fyn (218 to end) at 5 nM incubated for 15 mins relative to control | Homo sapiens | 3 | single protein format | Scientific Literature | ||
18. | ALA4839535 | B | Inhibition of human recombinant HCK (230 to 497) at 5 nM by radiometric scintillation counting analysis relative to control | Homo sapiens | 3 | single protein format | Scientific Literature | ||
19. | ALA4839536 | B | Inhibition of human full length recombinant IKKalpha at 5 nM by radiometric scintillation counting analysis relative to control | Homo sapiens | 3 | single protein format | Scientific Literature | ||
20. | ALA4839537 | B | Inhibition of human recombinant ITK (352 to 617) at 5 nM by radiometric scintillation counting analysis relative to control | Homo sapiens | 3 | single protein format | Scientific Literature |