| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4822732 | F | Anti-necroptotic activity in human HT-29 cells assessed as inhibition of TNFalpha/Z-VAD-fmk (TCZ)-induced necroptosis pretreated for 8 to 12 hrs | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 2. | ALA4822733 | B | Inhibition of human wild type RIPK1 (M1 to K305) expressed in bacterial system by kinomescan assay | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 3. | ALA4822734 | B | Inhibition of human wild type RIPK3 (M1 to Q307) expressed in bacterial system by kinomescan assay | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 4. | ALA4822735 | B | Inhibition of RIPK1 in human HT-29 cells assessed as inhibition of TSZ-induced RIPK1 phosphorylation at 1 uM measured upto 4 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA4822736 | B | Inhibition of RIPK1 in human HT-29 cells assessed as inhibition of TSZ-induced RIPK3 phosphorylation at 1 uM measured upto 4 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 6. | ALA4822737 | B | Inhibition of RIPK1 in human HT-29 cells assessed as inhibition of TSZ-induced MLKL phosphorylation at 1 uM measured upto 4 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA4822738 | B | Inhibition of RIPK1 in mouse L929 cells assessed as TZ-induced RIPK3 phosphorylation at 1 uM measured upto 4 hrs by Western blot analysis | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA4822739 | B | Inhibition of RIPK1 in mouse L929 cells assessed as TZ-induced MLKL phosphorylation at 1 uM measured upto 4 hrs by Western blot analysis | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA4822741 | F | Anti-necroptotic activity in human HT-29 cells assessed as inhibition of TSZ induced necroptosis at 0.25 uM measured after 12 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4822742 | F | Anti-necroptotic activity in mouse L929 cells assessed as inhibition of TZ-induced necroptosis measured after 9 hrs | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA4822743 | F | Anti-necroptotic activity in human HT-29 cells assessed as inhibition of TNFalpha/TS induced necroptosis uM measured after 36 hrs | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 12. | ALA4822746 | F | Anti-necroptotic activity in human HT-29 cells assessed as inhibition of TSZ induced necroptosis at 2.5 uM measured after 12 hrs | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA4822747 | F | Anti-necroptotic activity in mouse L929 cells assessed as inhibition of mTNFalpha-induced necroptosis measured after 9 hrs | Mus musculus | 3 | cell-based format | Scientific Literature |
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