# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4825572 | B | Binding affinity to human galectin-1 assessed as dissociation constant by competitive fluorescence polarization assay | Homo sapiens | 8 | single protein format | Scientific Literature | ||
2. | ALA4825573 | B | Binding affinity to human galectin-2 assessed as dissociation constant by competitive fluorescence polarization assay | Homo sapiens | 10 | single protein format | Scientific Literature | ||
3. | ALA4825574 | B | Binding affinity to human galectin-3 assessed as dissociation constant by competitive fluorescence polarization assay | Homo sapiens | 11 | single protein format | Scientific Literature | ||
4. | ALA4825575 | B | Binding affinity to human galectin-4 N terminal domain assessed as dissociation constant by competitive fluorescence polarization assay | Homo sapiens | 10 | single protein format | Scientific Literature | ||
5. | ALA4825576 | B | Binding affinity to human galectin-4 C terminal domain assessed as dissociation constant by competitive fluorescence polarization assay | Homo sapiens | 11 | single protein format | Scientific Literature | ||
6. | ALA4825578 | B | Binding affinity to human galectin-8 N terminal domain assessed as dissociation constant by competitive fluorescence polarization assay | Homo sapiens | 11 | single protein format | Scientific Literature | ||
7. | ALA4825579 | B | Binding affinity to human galectin-8 C terminal domain assessed as dissociation constant by competitive fluorescence polarization assay | Homo sapiens | 10 | single protein format | Scientific Literature | ||
8. | ALA4825580 | B | Binding affinity to human galectin-9 N terminal domain assessed as dissociation constant by competitive fluorescence polarization assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
9. | ALA4825582 | B | Selectivity for human galectin-8N over human galectin-3 | Homo sapiens | 11 | assay format | Scientific Literature | ||
10. | ALA4825583 | B | Selectivity for human galectin-8N over human galectin-2 | Homo sapiens | 11 | assay format | Scientific Literature | ||
11. | ALA4825584 | B | Selectivity for human galectin-8N over human galectin-1 | Homo sapiens | 11 | assay format | Scientific Literature | ||
12. | ALA4825585 | F | Cytotoxicity against human K562 cells assessed as cell viability at 1 to 100 uM measured after 24 hrs by MTS assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
13. | ALA4825586 | F | Cytotoxicity against human MDA-MB-231 cells assessed as cell viability at 1 to 100 uM measured after 24 hrs by MTS assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
14. | ALA4825587 | A | Cytotoxicity against human PBMC cells assessed as cell viability upto 100 uM measured after 24 hrs by MTS assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
15. | ALA4825588 | B | Antagonist activity at galactin-8 in human MDA-MB-231 cells assessed as reduction in IL-6 secretion at 10 uM measured after 24 hrs by flow cytometry relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
16. | ALA4825589 | B | Antagonist activity at galactin-8 in human MDA-MB-231 cells assessed as reduction in IL-6 secretion at 100 uM measured after 24 hrs by flow cytometry relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
17. | ALA4825590 | B | Antagonist activity at galactin-8 in human MDA-MB-231 cells assessed as reduction in IL-8 secretion at 10 uM measured after 24 hrs by flow cytometry relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
18. | ALA4825591 | B | Antagonist activity at galactin-8 in human MDA-MB-231 cells assessed as reduction in IL-8 secretion at 100 uM measured after 24 hrs by flow cytometry relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
19. | ALA4825595 | B | Binding affinity to human galectin-7 assessed as dissociation constant measured up to 1500 uM by competitive fluorescence polarization assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
20. | ALA4825598 | B | Binding affinity to human galectin-9 C terminal domain assessed as dissociation constant measured up to 1500 uM by competitive fluorescence polarization assay | Homo sapiens | 5 | single protein format | Scientific Literature |