| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4817425 | T | Toxicity in ICR mouse assessed as effect on lungs morphology at 100 uM, iv measured after 24 hrs by H and E staining based light microscopic analysis | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 2. | ALA4817426 | T | Toxicity in ICR mouse assessed as effect on heart morphology at 100 uM, iv measured after 24 hrs by H and E staining based light microscopic analysis | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 3. | ALA4817427 | T | Toxicity in ICR mouse assessed as effect on spleen morphology at 100 uM, iv measured after 24 hrs by H and E staining based light microscopic analysis | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 4. | ALA4817428 | F | Anti-metastatic activity against mouse 4T1 cells xenografted in BALB/c mouse assessed as metastasized area in lungs at 2.4 mg/kg, iv dosed every 3 days for 23 days and measured on day 30 by hematoxylin and eosin staining based analysis (Rvb = 44.8%) | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 5. | ALA4817429 | A | Time-dependent drug uptake in mouse 4T1 cells measured for 24 hrs by flow cytometric analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4817430 | A | Drug uptake in human MDA-MB-231 cells by flow cytometric analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA4817431 | A | Drug uptake in human L02 cells by flow cytometric analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA4817432 | F | Cytotoxicity against mouse 4T1 cells by MTT assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4817433 | F | Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability at 0.5 uM by calcein-AM/PI staining based fluorescence analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4817434 | F | Phototoxicity against human MDA-MB-231 cells assessed as reduction in cell viability at 0.5 uM in presence of illumination by calcein-AM/PI staining based fluorescence analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4817435 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as early apoptotic cells at 2.5 uM by flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4817436 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as necrotic cells at 2.5 uM by flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4817437 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as early apoptotic cells at 0.25 uM in presence of illumination by flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4817438 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as necrotic cells at 0.25 uM in presence of illumination by flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4817439 | A | Drug localization in lysosomes of human MDA-MB-231 cells at 0.5 uM by DAPI staining based confocal laser scanning microscopic method | Homo sapiens | 1 | subcellular format | Scientific Literature | ||
| 16. | ALA4817440 | A | Drug localization in mitochondria of human MDA-MB-231 cells at 0.5 uM by DAPI staining based confocal laser scanning microscopic method | Homo sapiens | 1 | mitochondrion format | Scientific Literature | ||
| 17. | ALA4817441 | A | Drug uptake in tumor of BALB/c mouse xenografted with mouse 4T1 cells at 100 uM, iv measured after 120 hrs by fluorescence molecular tomography | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA4817442 | F | Antitumor activity against mouse 4T1 cells xenografted in BALB/c mouse assessed as inhibition of tumor growth at 2.4 mg/kg, iv dosed every 3 days for 23 days | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 19. | ALA4817443 | F | Antitumor activity against mouse 4T1 cells xenografted in BALB/c mouse assessed as reduction in tumor weight at 2.4 mg/kg, iv dosed every 3 days for 23 days and measured on day 23 | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 20. | ALA4817444 | T | Toxicity in ICR mouse assessed as effect on kidney morphology at 100 uM, iv measured after 24 hrs by H and E staining based light microscopic analysis | Mus musculus | 2 | organism-based format | Scientific Literature |
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