| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4835172 | B | Inhibition of human recombinant ADAMTS-5 assessed as cleavage of fluorescent substrate using FAM-TBIS-1 by biochemical assay | Homo sapiens | 60 | single protein format | Scientific Literature | ||
| 2. | ALA4835173 | B | Inhibition of rat recombinant ADAMTS-5 assessed as cleavage of fluorescent substrate using FAM-TBIS-1 by biochemical assay | Rattus norvegicus | 4 | assay format | Scientific Literature | ||
| 3. | ALA4835174 | B | Inhibition of human recombinant ADAMTS-1 (AA253 to 734) assessed as cleavage of fluorescent substrate using 5(6)-fluorescein-NH-AELQGRPISIAK-5(6)-TAMRA as substrate incubated for 120 mins by biochemical assay | Homo sapiens | 15 | single protein format | Scientific Literature | ||
| 4. | ALA4835175 | B | Inhibition of human recombinant ADAMTS-4 (AA1 to 520) assessed as cleavage of fluorescent substrate using as TBIS-1 substrate incubated for 180 mins by biochemical assay | Homo sapiens | 14 | single protein format | Scientific Literature | ||
| 5. | ALA4835191 | A | Intrinsic clearance in human liver microsomes | Homo sapiens | 4 | microsome format | Scientific Literature | ||
| 6. | ALA4835192 | A | Intrinsic clearance in rat liver microsomes | Rattus norvegicus | 4 | microsome format | Scientific Literature | ||
| 7. | ALA4835193 | A | Inhibition of CYP1A2 (unknown origin) at 10 uM | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 8. | ALA4835194 | A | Inhibition of CYP1C19 (unknown origin) at 10 uM | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 9. | ALA4835195 | A | Inhibition of CYP2C9 (unknown origin) at 10 uM | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 10. | ALA4835196 | A | Inhibition of CYP2D6 (unknown origin) at 10 uM | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 11. | ALA4835197 | A | Inhibition of CYP3A4 (unknown origin) using BFC as substrate at 10 uM | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 12. | ALA4835198 | A | Inhibition of CYP3A4 (unknown origin) using DBF as substrate at 10 uM | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 13. | ALA4835199 | A | Plasma protein binding in rat at 5 uM measured after 4 hrs by LC-MS/MS analysis | Rattus norvegicus | 4 | cell-free format | Scientific Literature | ||
| 14. | ALA4835200 | A | Efflux ratio of apparent permeability in MDCK cells | Canis lupus familiaris | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4835201 | A | Cytotoxicity against human PBMC cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4835202 | A | Cytotoxicity against HEK cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4835203 | B | Inhibition of human ERG expressed in HEK293 cells measured at holding potential -80 mV at 10 uM by whole cell patch clam method | Homo sapiens | 4 | cell-based format | Scientific Literature |
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