# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4821680 | Functional | Antiproliferative activity against human NCI-H1299 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 42 | ALA4819081 | cell-based format | Scientific Literature | |
2. | ALA4821681 | Functional | Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 42 | ALA4819081 | cell-based format | Scientific Literature | |
3. | ALA4821682 | Functional | Antiproliferative activity against human MDA-MB-453 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 42 | ALA4819081 | cell-based format | Scientific Literature | |
4. | ALA4821683 | Functional | Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 42 | ALA4819081 | cell-based format | Scientific Literature | |
5. | ALA4821684 | Functional | Inhibition of clone formation in human MDA-MB-231 cells at 0.16 uM after 14 days by crystal violet staining based-colony formation assay | Homo sapiens | 1 | ALA4819081 | cell-based format | Scientific Literature | |
6. | ALA4821685 | Functional | Inhibition of clone formation in human MDA-MB-231 cells at 0.625 uM after 14 days by crystal violet staining based-colony formation assay | Homo sapiens | 1 | ALA4819081 | cell-based format | Scientific Literature | |
7. | ALA4821686 | ADME | Cytotoxicity against human L02 cells measured upto 20 uM after 72 hrs by MTT assay | Homo sapiens | 1 | ALA4819081 | cell-based format | Scientific Literature | |
8. | ALA4821687 | Binding | Inhibition of CDK4/Cyclin D1 (unknown origin) at 200 nM using ATP by mobility shift assay | Homo sapiens | 12 | ALA4819081 | protein complex format | Scientific Literature | |
9. | ALA4821688 | Binding | Inhibition of CDK4/Cyclin D1 (unknown origin) at 20 nM using ATP by mobility shift assay | Homo sapiens | 12 | ALA4819081 | protein complex format | Scientific Literature | |
10. | ALA4821689 | Binding | Inhibition of CDK6/Cyclin D3 (unknown origin) at 200 nM using ATP by mobility shift assay | Homo sapiens | 12 | ALA4819081 | protein complex format | Scientific Literature | |
11. | ALA4821690 | Binding | Inhibition of CDK6/Cyclin D3 (unknown origin) at 20 nM using ATP by mobility shift assay | Homo sapiens | 12 | ALA4819081 | protein complex format | Scientific Literature | |
12. | ALA4821691 | Binding | Inhibition of CDK4/6 in human MDA-MB-231 cells assessed as reduction in Rb phosphorylation at Ser780 after 24 hrs by western blot analysis | Homo sapiens | 1 | ALA4819081 | cell-based format | Scientific Literature | |
13. | ALA4821692 | Binding | Inhibition of CDK6/Cyclin D3 (unknown origin) by mobility shift assay | Homo sapiens | 2 | ALA4819081 | protein complex format | Scientific Literature | |
14. | ALA4821693 | Binding | Inhibition of CDK4/Cyclin D3 (unknown origin) by mobility shift assay | Homo sapiens | 2 | ALA4819081 | protein complex format | Scientific Literature | |
15. | ALA4821694 | Functional | Induction of cell cycle arrest in human MDA-MB-231 cells assessed as accumulation at G1 phase at 0.1875 uM after 12 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 53.11%) | Homo sapiens | 1 | ALA4819081 | cell-based format | Scientific Literature | |
16. | ALA4821695 | Functional | Induction of cell cycle arrest in human MDA-MB-231 cells assessed as accumulation at S phase at 0.1875 uM after 12 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 23.71%) | Homo sapiens | 1 | ALA4819081 | cell-based format | Scientific Literature | |
17. | ALA4821696 | Functional | Induction of cell cycle arrest in human MDA-MB-231 cells assessed as accumulation at S phase at 0.1875 uM after 12 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 21.11%) | Homo sapiens | 1 | ALA4819081 | cell-based format | Scientific Literature | |
18. | ALA4821697 | Functional | Induction of cell cycle arrest in human MDA-MB-231 cells assessed as accumulation at G1 phase at 0.375 uM after 12 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 53.11%) | Homo sapiens | 1 | ALA4819081 | cell-based format | Scientific Literature | |
19. | ALA4821698 | Functional | Induction of cell cycle arrest in human MDA-MB-231 cells assessed as accumulation at S phase at 0.375 uM after 12 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 23.71%) | Homo sapiens | 1 | ALA4819081 | cell-based format | Scientific Literature | |
20. | ALA4821699 | Functional | Induction of cell cycle arrest in human MDA-MB-231 cells assessed as accumulation at S phase at 0.375 uM after 12 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 21.11%) | Homo sapiens | 1 | ALA4819081 | cell-based format | Scientific Literature |