# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4821680 | F | Antiproliferative activity against human NCI-H1299 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 42 | cell-based format | Scientific Literature | ||
2. | ALA4821681 | F | Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 42 | cell-based format | Scientific Literature | ||
3. | ALA4821682 | F | Antiproliferative activity against human MDA-MB-453 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 42 | cell-based format | Scientific Literature | ||
4. | ALA4821683 | F | Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 42 | cell-based format | Scientific Literature | ||
5. | ALA4821684 | F | Inhibition of clone formation in human MDA-MB-231 cells at 0.16 uM after 14 days by crystal violet staining based-colony formation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA4821685 | F | Inhibition of clone formation in human MDA-MB-231 cells at 0.625 uM after 14 days by crystal violet staining based-colony formation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA4821686 | A | Cytotoxicity against human L02 cells measured upto 20 uM after 72 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
8. | ALA4821687 | B | Inhibition of CDK4/Cyclin D1 (unknown origin) at 200 nM using ATP by mobility shift assay | Homo sapiens | 12 | protein complex format | Scientific Literature | ||
9. | ALA4821688 | B | Inhibition of CDK4/Cyclin D1 (unknown origin) at 20 nM using ATP by mobility shift assay | Homo sapiens | 12 | protein complex format | Scientific Literature | ||
10. | ALA4821689 | B | Inhibition of CDK6/Cyclin D3 (unknown origin) at 200 nM using ATP by mobility shift assay | Homo sapiens | 12 | protein complex format | Scientific Literature | ||
11. | ALA4821690 | B | Inhibition of CDK6/Cyclin D3 (unknown origin) at 20 nM using ATP by mobility shift assay | Homo sapiens | 12 | protein complex format | Scientific Literature | ||
12. | ALA4821691 | B | Inhibition of CDK4/6 in human MDA-MB-231 cells assessed as reduction in Rb phosphorylation at Ser780 after 24 hrs by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
13. | ALA4821692 | B | Inhibition of CDK6/Cyclin D3 (unknown origin) by mobility shift assay | Homo sapiens | 2 | protein complex format | Scientific Literature | ||
14. | ALA4821693 | B | Inhibition of CDK4/Cyclin D3 (unknown origin) by mobility shift assay | Homo sapiens | 2 | protein complex format | Scientific Literature | ||
15. | ALA4821694 | F | Induction of cell cycle arrest in human MDA-MB-231 cells assessed as accumulation at G1 phase at 0.1875 uM after 12 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 53.11%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
16. | ALA4821695 | F | Induction of cell cycle arrest in human MDA-MB-231 cells assessed as accumulation at S phase at 0.1875 uM after 12 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 23.71%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
17. | ALA4821696 | F | Induction of cell cycle arrest in human MDA-MB-231 cells assessed as accumulation at S phase at 0.1875 uM after 12 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 21.11%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
18. | ALA4821697 | F | Induction of cell cycle arrest in human MDA-MB-231 cells assessed as accumulation at G1 phase at 0.375 uM after 12 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 53.11%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
19. | ALA4821698 | F | Induction of cell cycle arrest in human MDA-MB-231 cells assessed as accumulation at S phase at 0.375 uM after 12 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 23.71%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
20. | ALA4821699 | F | Induction of cell cycle arrest in human MDA-MB-231 cells assessed as accumulation at S phase at 0.375 uM after 12 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 21.11%) | Homo sapiens | 1 | cell-based format | Scientific Literature |