#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4836937	Binding	Binding affinity to human partial length BCL2A1 (M1 to G153 residues) expressed in bacterial expression system by BCL2SCAN assay	Homo sapiens	1	ALA4834480	assay format	Scientific Literature
2.	ALA4836939	Binding	Binding affinity to human partial length BCLW (M1 to R171 residues) expressed in bacterial expression system by BCL2SCAN assay	Homo sapiens	1	ALA4834480	assay format	Scientific Literature
3.	ALA4836940	Binding	Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 30 mins fluorescence polarization-based competitive binding assay	Homo sapiens	49	ALA4834480	assay format	Scientific Literature
4.	ALA4836942	ADME	Permeability of the compound at pH 7.4 measured after 4 hrs by PAMPA assay		1	ALA4834480	assay format	Scientific Literature
5.	ALA4836943	Physicochemical	Water solubility of the compound		1	ALA4834480	small-molecule physicochemical format	Scientific Literature
6.	ALA4836944	Binding	Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged BCL2 (1 to 205 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) at 10 uM incubated for 30 mins fluorescence polarization-based competitive binding assay relative to control	Homo sapiens	5	ALA4834480	assay format	Scientific Literature
7.	ALA4836945	Binding	Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged BFL1 (1 to 151 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) at 10 uM incubated for 30 mins fluorescence polarization-based competitive binding assay relative to control	Homo sapiens	4	ALA4834480	assay format	Scientific Literature
8.	ALA4836946	Binding	Binding affinity to human partial length MCL1 (D172N to R329 residues) expressed in bacterial expression system by BCL2SCAN assay	Homo sapiens	1	ALA4834480	assay format	Scientific Literature
9.	ALA4836947	Binding	Binding affinity to human partial length BCL2 (M1 to D211 residues) expressed in bacterial expression system by BCL2SCAN assay	Homo sapiens	1	ALA4834480	assay format	Scientific Literature
10.	ALA4836948	Binding	Binding affinity to human partial length BCL-XL (M1 to R209 residues) expressed in bacterial expression system by BCL2SCAN assay	Homo sapiens	1	ALA4834480	assay format	Scientific Literature
11.	ALA4836949	Binding	Selectivity ratio of Kd for human partial length BCL2 (M1 to D211 residues) expressed in bacterial expression system to Kd for human partial length MCL1 (D172N to R329 residues) expressed in bacterial expression system	Homo sapiens	1	ALA4834480	assay format	Scientific Literature
12.	ALA4836950	Functional	Antiproliferative activity against human NCI-H929 cells assessed as decrease in cell viability measured after 72 hrs by MTT assay	Homo sapiens	8	ALA4834480	cell-based format	Scientific Literature
13.	ALA4836951	Functional	Antiproliferative activity against human MV4-11 cells assessed as decrease in cell viability measured after 72 hrs by MTT assay	Homo sapiens	8	ALA4834480	cell-based format	Scientific Literature
14.	ALA4836952	Functional	Antiproliferative activity against human SK-BR-3 cells assessed as decrease in cell viability measured after 72 hrs by MTT assay	Homo sapiens	8	ALA4834480	cell-based format	Scientific Literature
15.	ALA4836953	Functional	Antiproliferative activity against human NCI-H23 cells assessed as decrease in cell viability measured after 72 hrs by MTT assay	Homo sapiens	8	ALA4834480	cell-based format	Scientific Literature
16.	ALA4836954	Functional	Antiproliferative activity against human K562 cells assessed as decrease in cell viability measured after 72 hrs by MTT assay	Homo sapiens	8	ALA4834480	cell-based format	Scientific Literature
17.	ALA4836955	Binding	Displacement of BAK from MCL1 in human NCI-H929 cells after 4 hrs by co-immunoprecipitation assay	Homo sapiens	1	ALA4834480	cell-based format	Scientific Literature
18.	ALA4836956	Functional	Induction of apoptosis in human NCI-H929 cells measured after 48 hrs by annexinV-FITC/propidium iodide staining based flow cytometry analysis	Homo sapiens	2	ALA4834480	cell-based format	Scientific Literature
19.	ALA4836957	Functional	Induction of apoptosis in human NCI-H929 cells assessed as upregulation of cleaved PARP measured after 48 hrs by Western blot analysis	Homo sapiens	2	ALA4834480	cell-based format	Scientific Literature
20.	ALA4836958	Functional	Induction of apoptosis in human K562 cells assessed as upregulation of cleaved PARP up to 5 uM measured after 48 hrs by Western blot analysis	Homo sapiens	2	ALA4834480	cell-based format	Scientific Literature