# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA637489 | P | Partition coefficient was evaluated using method of Morgiuchi et al | 19 | small-molecule physicochemical format | Scientific Literature | |||
2. | ALA744711 | F | Minimum inhibitory concentration against Mtb H37Rv using Middlebrook 7H9 with glycerol and OADC enrichment | Mycobacterium tuberculosis | 18 | assay format | Scientific Literature | ||
3. | ALA998774 | F | Antagonist activity at HA-tagged mouse AT1a angiotensin 2 receptor expressed in HEK293T cells assessed as decrease in angiotensin 2-induced intracellular calcium uptake | 45 | cell-based format | Scientific Literature | |||
4. | ALA998775 | A | Cytotoxicity against HEK293T cells expressing HA-tagged mouse AT1a angiotensin 2 receptor up to 100 ug/ml after 24 hrs by trypan blue dye exclusion assay | Homo sapiens | 43 | cell-based format | Scientific Literature | ||
5. | ALA2439164 | F | Antiproliferative activity against human DLD1 cells assessed as cell viability at 100 uM after 72 hrs by MTT assay in presence of Escherichia coli NTR and NADPH (Rvb = 107.4%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA2439165 | F | Antiproliferative activity against human DLD1 cells assessed as cell viability at 50 uM after 72 hrs by MTT assay in presence of Escherichia coli NTR and NADPH (Rvb = 107.4%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA2439167 | F | Antiproliferative activity against human DLD1 cells assessed as cell viability at 100 uM after 72 hrs by MTT assay in absence of Escherichia coli NTR and NADPH (Rvb = 107.4%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
8. | ALA2439168 | F | Antiproliferative activity against human DLD1 cells assessed as cell viability at 50 uM after 72 hrs by MTT assay in absence of Escherichia coli NTR and NADPH (Rvb = 107.4%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
9. | ALA2439170 | F | Antiproliferative activity against human DLD1 cells assessed as cell viability at 25 uM after 72 hrs by MTT assay in absence of Escherichia coli NTR and NADPH (Rvb = 107.4%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
10. | ALA2439179 | F | Cytotoxicity against human DLD1 cells assessed as cell viability at 25 uM after 72 hrs by MTT assay in presence of Escherichia coli NTR and NADPH (Rvb = 107.4%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
11. | ALA2439183 | P | Stability of the compound in phosphate buffer at pH 7.0 assessed as nitric oxide release at 50 uM after 1 hr by chemiluminescence assay in absence of Escherichia coli NTR and presence of NADPH | 5 | small-molecule physicochemical format | Scientific Literature | |||
12. | ALA2439184 | P | Prodrug conversion in phosphate buffer at pH 7.0 assessed as Escherichia coli NTR-mediated decomposition measuring nitric oxide release at 50 uM after 1 hr by chemiluminescence assay in presence of NADPH | Escherichia coli | 5 | small-molecule physicochemical format | Scientific Literature | ||
13. | ALA2439185 | P | Prodrug conversion in phosphate buffer at pH 7.0 assessed as Escherichia coli NTR-mediated decomposition measuring compound remaining at 50 uM after 1 hr by HPLC analysis in presence of NADPH | Escherichia coli | 5 | small-molecule physicochemical format | Scientific Literature | ||
14. | ALA2439311 | P | Stability of the compound in phosphate buffer at pH 7.0 assessed as compound remaining at 50 uM after 1 hr by HPLC analysis in absence of Escherichia coli NTR and presence of NADPH | 5 | small-molecule physicochemical format | Scientific Literature | |||
15. | ALA4320927 | A | Substrate activity at recombinant Haemophilus influenzae Chloramphenicol nitroreductase expressed in Escherichia coli assessed as initial rate of reaction at 150 uM measured at 30 sec interval for 5 mins in presence of NADPH at pH 8 under 37 degC by UV-visible assay relative to CAM | Haemophilus influenzae | 53 | assay format | Scientific Literature |