| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4821989 | B | Binding affinity to recombinant human His-tagged gankyrin expressed in Escherichia coli assessed as change in melting temperature at 300 uM by SYPRO orange dye based thermal shift assay | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 2. | ALA4821990 | B | Potency index, ratio of deltaTm of compound to deltaTm of Cjoc42 for binding affinity to recombinant human His-tagged gankyrin expressed in Escherichia coli at 300 uM by SYPRO orange dye based thermal shift assay | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 3. | ALA4821991 | F | Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 4. | ALA4821992 | F | Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA4821993 | F | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 6. | ALA4821994 | F | Cytotoxicity against human Hep3B cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA4821995 | F | Cytotoxicity against human HuH-6 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA4821996 | F | Potency index, ratio of IC50 of Cjoc42 to IC50 of compound for cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4821997 | F | Potency index, ratio of IC50 of Cjoc42 to IC50 of compound for cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4821998 | F | Potency index, ratio of IC50 of Cjoc42 to IC50 of compound for cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4821999 | F | Potency index, ratio of IC50 of Cjoc42 to IC50 of compound for cytotoxicity against human Hep3B cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4822000 | F | Potency index, ratio of IC50 of Cjoc42 to IC50 of compound for cytotoxicity against human HuH-6 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature |
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