#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4807191	F	Inhibition of mouse GPR174 in anti-CD3/antiCD28-stimulated mouse splenocytes assessed as increase in IL-2 production at 10 uM measured after 2 days	Mus musculus	1		tissue-based format	Patent Bioactivity Data
2.	ALA4807192	F	Inverse agonist activity at human GPR174 expressed in cells assessed as inhibition of CRE-luc reporter activity by measuring decrease in Gs-protein signalling activity relative to control	Homo sapiens	50		cell-based format	Patent Bioactivity Data
3.	ALA4807193	F	Inhibition of GPR174 (unknown origin) in cells assessed as incorporation of nuclear localization sequence into transmembrane protein by cellular redistribution assay	Homo sapiens	26		assay format	Patent Bioactivity Data
4.	ALA4807194	F	Inverse agonist activity at human GPR174 expressed in cells assessed as inhibition of CRE-luc reporter activity by measuring decrease in Gs-protein signalling activity	Homo sapiens	50		cell-based format	Patent Bioactivity Data
5.	ALA4807195	F	Inhibition of GPR174 in anti-CD3/antiCD28-stimulated human PBMC assessed as increase in IFNgamma level measured after 2 days by ELISA	Homo sapiens	1		tissue-based format	Patent Bioactivity Data
6.	ALA4807196	F	Inhibition of human GPR174 in anti-CD3/antiCD28-stimulated human PBMC assessed as increase in IL-2 level measured after 2 days by ELISA	Homo sapiens	2		tissue-based format	Patent Bioactivity Data
7.	ALA4807199	F	Inhibition of human GPR174 in anti-CD3/antiCD28-stimulated human PBMC assessed as increase in natural Treg cells (FoxP3+Helios-) at 100 uM measure after 7 days by flow cytometry	Homo sapiens	1		cell-based format	Patent Bioactivity Data
8.	ALA4807200	F	Inhibition of human GPR174 in anti-CD3/antiCD28-stimulated human PBMC assessed as reduction in natural Treg cells (FoxP3+Helios+) at 100 uM measure after 7 days by flow cytometry	Homo sapiens	1		cell-based format	Patent Bioactivity Data
9.	ALA4807201	F	Inhibition of human GPR174 in anti-CD3/antiCD28-stimulated human PBMC assessed as reduction in natural Treg cells (FoxP3+Helios+) measure after 7 days by ELISA	Homo sapiens	1		cell-based format	Patent Bioactivity Data
10.	ALA4807202	F	Effect on IL-2 production in mouse GPR174 knock out splenocytes at 10 uM measured after 2 days	Mus musculus	1		cell-based format	Patent Bioactivity Data
11.	ALA4807203	F	Inhibition of human GPR174 in anti-CD3/antiCD28-stimulated human PBMC assessed as increase in IL-2 production measured after 2 days	Homo sapiens	1		tissue-based format	Patent Bioactivity Data
12.	ALA4807204	F	Inhibition of human GPR174 in anti-CD3/antiCD28-stimulated human PBMC assessed as increase in IL-6 production at 10 uM measured after 2 days relative to control	Homo sapiens	1		tissue-based format	Patent Bioactivity Data
13.	ALA4807205	F	Inhibition of human GPR174 in anti-CD3/antiCD28-stimulated human PBMC assessed as increase in IL-10 production at 10 uM measured after 2 days relative to control	Homo sapiens	1		tissue-based format	Patent Bioactivity Data
14.	ALA4807206	F	Inhibition of human GPR174 in anti-CD3/antiCD28-stimulated human PBMC assessed as increase in IFNgamma production at 10 uM measured after 2 days relative to control	Homo sapiens	1		tissue-based format	Patent Bioactivity Data
15.	ALA4807207	F	Inhibition of human GPR174 in anti-CD3/antiCD28-stimulated human PBMC assessed as increase in TNFalpha production at 10 uM measured after 2 days relative to control	Homo sapiens	1		tissue-based format	Patent Bioactivity Data
16.	ALA4807208	F	Inhibition of human GPR174 in anti-CD3/antiCD28-stimulated human PBMC assessed as CD4+ cell population at 10 uM measured after 2 days relative to control	Homo sapiens	1		tissue-based format	Patent Bioactivity Data
17.	ALA4807209	F	Inhibition of human GPR174 in anti-CD3/antiCD28-stimulated human PBMC assessed as CD8+ cell population at 10 uM measured after 2 days relative to control	Homo sapiens	1		tissue-based format	Patent Bioactivity Data
18.	ALA4807210	F	Inhibition of human GPR174 in anti-CD3/antiCD28-stimulated human PBMC assessed as non-T cell cell population at 10 uM measured after 2 days relative to control	Homo sapiens	1		tissue-based format	Patent Bioactivity Data
19.	ALA4807211	F	Inhibition of human GPR174 in anti-CD3/antiCD28-stimulated human regulatory T cells assessed as reduction in CTLA4 expression relative to control	Homo sapiens	1		tissue-based format	Patent Bioactivity Data
20.	ALA4807212	F	Inhibition of human GPR174 in anti-CD3/antiCD28-stimulated human PBMC assessed as reduction in CTLA4 expression relative to control	Homo sapiens	1		tissue-based format	Patent Bioactivity Data