| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4844157 | A | Half life in human serum at 100 uM by RP-HPLC method | Homo sapiens | 1 | cell-free format | Scientific Literature | ||
| 2. | ALA4844173 | B | Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf RBD interaction incubated for 1 hr by HTRF assay | Homo sapiens | 65 | cell-based format | Scientific Literature | ||
| 3. | ALA4844174 | F | Antiproliferative activity against human NCI-H358 cells incubated for 96 hrs by Celltiter-Glo assay | Homo sapiens | 48 | cell-based format | Scientific Literature | ||
| 4. | ALA4844175 | B | Binding affinity to GTPgammaS bound His6-tagged KRas G12V mutant (unknown origin) incubated for 1 hr by fluorescence polarization | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 5. | ALA4844176 | B | Binding affinity to GppNHp bound His6-tagged KRas G12V mutant (unknown origin) incubated for 1 hr by fluorescence polarization | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 6. | ALA4844177 | B | Binding affinity to GDP bound His6-tagged KRas G12V mutant (unknown origin) incubated for 1 hr by fluorescence polarization | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA4844178 | A | Binding affinity to bovine serum albumin | Bos taurus | 1 | single protein format | Scientific Literature | ||
| 8. | ALA4844179 | B | Binding affinity to glutathione-S-transferase (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 9. | ALA4844180 | B | Binding affinity to purine nucleoside phosphorylase (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA4844181 | B | Binding affinity to PTP1B (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA4844182 | B | Binding affinity to MDM2 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 12. | ALA4844183 | A | Drug localization in human HeLa cells assessed as mean fluorescence intensity at 5 uM incubated for 2 hrs in presence of 1% FBS by flow cytometry relative to CPP12 | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4844185 | A | Drug distribution in human HeLa cells assessed as diffuse fluorescence throughout the entire cell volume at 5 uM incubated for 2 hrs by live-cell confocal microscopy | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4844186 | A | Drug distribution in human HeLa cells assessed as fluorescent puncta in cytoplasmic region at 5 uM incubated for 2 hrs by live-cell confocal microscopy | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4844187 | A | Drug distribution in human NCI-H358 cells assessed as diffuse fluorescence throughout the entire cell volume at 5 uM incubated for 2 hrs by live-cell confocal microscopy | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4844188 | A | Drug distribution in human NCI-H358 cells assessed as fluorescent puncta in cytoplasmic region at 5 uM incubated for 2 hrs by live-cell confocal microscopy | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4844189 | A | Drug distribution in human A549 cells assessed as diffuse fluorescence throughout the entire cell volume at 5 uM incubated for 2 hrs by live-cell confocal microscopy | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4844190 | A | Drug distribution in human A549 cells assessed as fluorescent puncta in cytoplasmic region at 5 uM incubated for 2 hrs by live-cell confocal microscopy | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4844191 | A | Drug distribution in human NCI-H358 cells assessed as accumulation in plasma membrane at 5 uM incubated for 2 hrs by live-cell confocal microscopy | Homo sapiens | 1 | cell membrane format | Scientific Literature | ||
| 20. | ALA4844192 | A | Drug distribution in human A549 cells assessed as accumulation in plasma membrane at 5 uM incubated for 2 hrs by live-cell confocal microscopy | Homo sapiens | 1 | cell membrane format | Scientific Literature |
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