# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4831867 | F | Cytotoxicity against human A549 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
2. | ALA4831868 | B | Inhibition of Tak1/Tab1 (unknown origin) assessed as inhibition of Tak1 kinase activity preincubated for 30 mins followed by addition of MBP protein and ATP and measured after 2 hrs by ADP-Glo kinase assay | Homo sapiens | 11 | protein format | Scientific Literature | ||
3. | ALA4831869 | B | Inhibition of NF-kB (unknown origin) expressed in HEK293T cells transfected with pTK-Renilla reporter preincubated for 6 hrs followed by addition of TNF-alpha and measured after 8 hrs by Dual luciferase reporter assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
4. | ALA4831876 | F | Cell cycle arrest in human A549 cells assessed as accumulation at G0/G1 phase at 1.8 uM measured after 24 hrs by PI staining based Flow cytometry method (Rvb = 55.54%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
5. | ALA4831877 | F | Cell cycle arrest in human A549 cells assessed as accumulation at G2/M phase at 1.8 uM measured after 24 hrs by PI staining based Flow cytometry method (Rvb = 10.2%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
6. | ALA4831878 | F | Cell cycle arrest in human A549 cells assessed as accumulation at S phase at 1.8 uM measured after 24 hrs by PI staining based Flow cytometry method (Rvb = 34.24%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
7. | ALA4831888 | F | Induction of apoptosis in human A549 cells assessed as viable cells at 1.8 uM measured by annexinV-FITC/propidium iodide staining based flow cytometry analysis (Rvb = 97.8%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
8. | ALA4831889 | F | Induction of apoptosis in human A549 cells assessed as early apoptotic cells at 1.8 uM measured by annexinV-FITC/propidium iodide staining based flow cytometry analysis (Rvb = 1.17%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
9. | ALA4831890 | F | Induction of apoptosis in human A549 cells assessed as late apoptotic cells at 1.8 uM measured by annexinV-FITC/propidium iodide staining based flow cytometry analysis (Rvb = 0.64%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
10. | ALA4831891 | F | Induction of apoptosis in human A549 cells assessed as necrotic cells at 1.8 uM measured by annexinV-FITC/propidium iodide staining based flow cytometry analysis (Rvb = 0.42%) | Homo sapiens | 2 | cell-based format | Scientific Literature |