| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4832929 | B | Protac activity at IAP/RIPK2 in human whole blood assessed as inhibition of MDP-induced TNFalpha production by ELISA | Homo sapiens | 20 | tissue-based format | Scientific Literature | ||
| 2. | ALA4832930 | P | Solubility of the compound by chemiluminescent nitrogen detection (CLND) method | 15 | small-molecule physicochemical format | Scientific Literature | |||
| 3. | ALA4832931 | P | Lipophilicity, logD of compound at pH 7.4 by Chromatography | 20 | small-molecule physicochemical format | Scientific Literature | |||
| 4. | ALA4832932 | A | Metabolic stability in human liver microsomes assessed as intrinsic clearance using pH 7.4 phosphate buffer incubated for 45 mins by LC-MS/MS analysis | Homo sapiens | 11 | microsome format | Scientific Literature | ||
| 5. | ALA4832933 | A | Metabolic stability in rat liver microsomes assessed as intrinsic clearance using pH 7.4 phosphate buffer incubated for 45 mins by LC-MS/MS analysis | Rattus norvegicus | 11 | microsome format | Scientific Literature | ||
| 6. | ALA4832944 | B | Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive ligand by fluorescent polarization based binding assay | Homo sapiens | 22 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!