| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4815607 | B | Selectivity index, ratio of pKi for displacement of [3H]NMS from human recombinant muscarinic receptor M3 expressed in CHO cell membranes to pKi for displacement of [3H]NMS from human recombinant muscarinic receptor M2 expressed in CHO cell membranes | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
| 2. | ALA4815608 | B | Selectivity index, ratio of pKi for displacement of [3H]NMS from human recombinant muscarinic receptor M1 expressed in CHO cell membranes to pKi for displacement of [3H]NMS from human recombinant muscarinic receptor M2 expressed in CHO cell membranes | Homo sapiens | 76 | cell-based format | Scientific Literature | ||
| 3. | ALA4815609 | B | Displacement of [3H]-NMS from human muscarinic M1 receptor expressed in CHO cell membranes assessed as inhibition constant by radioligand competition analysis | Homo sapiens | 76 | cell membrane format | Scientific Literature | ||
| 4. | ALA4815610 | B | Displacement of [3H]-NMS from human muscarinic M2 receptor expressed in CHO cell membranes assessed as inhibition constant by radioligand competition analysis | Homo sapiens | 79 | cell membrane format | Scientific Literature | ||
| 5. | ALA4815611 | B | Displacement of [3H]-NMS from human muscarinic M3 receptor expressed in CHO cell membranes assessed as inhibition constant by radioligand competition analysis | Homo sapiens | 30 | cell membrane format | Scientific Literature | ||
| 6. | ALA4815612 | B | Displacement of [3H]-NMS from human muscarinic M4 receptor expressed in CHO cell membranes assessed as inhibition constant by radioligand competition analysis | Homo sapiens | 76 | cell membrane format | Scientific Literature | ||
| 7. | ALA4815613 | B | Displacement of [3H]-NMS from human muscarinic M5 receptor expressed in CHO cell membranes assessed as inhibition constant by radioligand competition analysis | Homo sapiens | 29 | cell membrane format | Scientific Literature | ||
| 8. | ALA4815614 | B | Selectivity index, ratio of pKi for displacement of [3H]NMS from human recombinant muscarinic receptor M4 expressed in CHO cell membranes to pKi for displacement of [3H]NMS from human recombinant muscarinic receptor M2 expressed in CHO cell membranes | Homo sapiens | 76 | cell-based format | Scientific Literature | ||
| 9. | ALA4815615 | B | Selectivity index, ratio of pKi for displacement of [3H]NMS from human recombinant muscarinic receptor M5 expressed in CHO cell membranes to pKi for displacement of [3H]NMS from human recombinant muscarinic receptor M2 expressed in CHO cell membranes | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
| 10. | ALA4815616 | F | Antagonist activity at human muscarinic acetylcholine receptor M2 expressed in human HEK293T cells coexpressing NlucN-mini-Gsi assessed as inhibition of iperoxo-induced mini-Gsi recruitment by measuring equilibrium binding constant by nano-luciferase technique | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA4815618 | F | Antagonist activity at human muscarinic acetylcholine receptor M2 expressed in human HEK293T cells coexpressing NlucN-mini-Gsi assessed as inhibition of iperoxo-induced mini-Gsi recruitment by measuring right ward shift of iperoxo-concentration-response curves at 16 uM preincubated for 120 mins followed by iperoxo-addition and measured by nano-luciferase technique | Homo sapiens | 1 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!