| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4836856 | F | Antiproliferative activity against human SU-DHL-5 cells assessed as cell viability at 10 uM by CellTiter-Glo luminescent cell viability assay (Rvb = 100%) | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 2. | ALA4836857 | F | Antiproliferative activity against human MOLT-4 cells assessed as cell viability at 20 uM by CellTiter-Glo luminescent cell viability assay (Rvb = 100%) | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 3. | ALA4836858 | B | Inhibition of recombinant human full length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system measured after 60 mins in presence of ATP by ATP-competitive binding assay | Homo sapiens | 16 | assay format | Scientific Literature | ||
| 4. | ALA4836859 | B | Inhibition of recombinant human full length His-tagged p110beta expressed in baculovirus expression system measured after 60 mins in presence of ATP by ATP-competitive binding assay | Homo sapiens | 16 | assay format | Scientific Literature | ||
| 5. | ALA4836860 | B | Inhibition of recombinant human full length His-tagged p110gamma expressed in baculovirus expression system measured after 60 mins in presence of ATP by ATP-competitive binding assay | Homo sapiens | 16 | assay format | Scientific Literature | ||
| 6. | ALA4836861 | B | Inhibition of recombinant human full length His-tagged p110delta/p85alpha expressed in baculovirus expression system measured after 60 mins in presence of ATP by ATP-competitive binding assay | Homo sapiens | 16 | assay format | Scientific Literature | ||
| 7. | ALA4836862 | B | Selectivity ratio of IC50 for recombinant human full length His-tagged p110gamma expressed in baculovirus expression system to IC50 for recombinant human full length His-tagged p110delta/p85alpha expressed in baculovirus expression system | Homo sapiens | 16 | assay format | Scientific Literature | ||
| 8. | ALA4836863 | B | Inhibition of PI3Kdelta in human SU-DHL-5 cells assessed as inhibition of AKT phosphorylation at Ser473 residue at 1 to 5 uM measured after 3 hrs by western blot assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA4836864 | B | Inhibition of PI3Kdelta in human MOLT-4 cells assessed as inhibition of AKT phosphorylation at Ser473 residue at 1 to 5 uM measured after 3 hrs by western blot assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA4836865 | B | Inhibition of PI3Kdelta in human SU-DHL-5 cells assessed as inhibition of S6 phosphorylation at 1 to 5 uM measured after 3 hrs by western blot assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA4836866 | B | Inhibition of PI3Kdelta in human MOLT-4 cells assessed as inhibition of S6 phosphorylation at 1 to 5 uM measured after 3 hrs by western blot assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA4836867 | B | Inhibition of PI3Kdelta in human SU-DHL-5 cells assessed as inhibition of 4EBP1 phosphorylation at 1 to 5 uM measured after 3 hrs by western blot assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA4836868 | B | Inhibition of PI3Kdelta in human MOLT-4 cells assessed as inhibition of 4EBP1 phosphorylation at 1 to 5 uM measured after 3 hrs by western blot assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 14. | ALA4836869 | F | Induction of apoptosis in human SU-DHL-10 cells assessed as viable cells at 20 uM measured after 24 hrs by AnnexinV-FITC/PI staining based flowcytometry method (Rvb = 90%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 15. | ALA4836870 | F | Induction of apoptosis in human SU-DHL-10 cells assessed as early apoptotic cells at 20 uM measured after 24 hrs by AnnexinV-FITC/PI staining based flowcytometry method (Rvb = 6.32%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 16. | ALA4836871 | F | Induction of apoptosis in human SU-DHL-10 cells assessed as late apoptotic cells at 20 uM measured after 24 hrs by AnnexinV-FITC/PI staining based flowcytometry method (Rvb = 3.48%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 17. | ALA4836872 | F | Induction of apoptosis in human SU-DHL-10 cells assessed as necrotic cells at 20 uM measured after 24 hrs by AnnexinV-FITC/PI staining based flowcytometry method (Rvb = 0.2%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 18. | ALA4836873 | F | Induction of apoptosis in human MOLT-4 cells assessed as viable cells at 20 uM measured after 24 hrs by AnnexinV-FITC/PI staining based flowcytometry method (Rvb = 95.3%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 19. | ALA4836874 | F | Induction of apoptosis in human MOLT-4 cells assessed as early apoptotic cells at 20 uM measured after 24 hrs by AnnexinV-FITC/PI staining based flowcytometry method (Rvb = 2.04%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 20. | ALA4836875 | F | Induction of apoptosis in human MOLT-4 cells assessed as late apoptotic cells at 20 uM measured after 24 hrs by AnnexinV-FITC/PI staining based flowcytometry method (Rvb = 2.17%) | Homo sapiens | 3 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!