# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4840023 | Functional | Antibacterial activity against Staphylococcus aureus ATCC 29213 by CLSI method | Staphylococcus aureus | 41 | ALA4837261 | organism-based format | Scientific Literature | |
2. | ALA4840024 | Functional | Antibacterial activity against methicillin-resistant Staphylococcus aureus USA300 by CLSI method | Staphylococcus aureus | 41 | ALA4837261 | organism-based format | Scientific Literature | |
3. | ALA4840025 | Functional | Antibacterial activity against cystic fibrosis isolate Staphylococcus aureus by CLSI method | Staphylococcus aureus | 41 | ALA4837261 | organism-based format | Scientific Literature | |
4. | ALA4840031 | Binding | Inhibition of Staphylococcus aureus Gyrase supercoiling activity assessed as reduction in supercoiling pBR322 DNA by measuring relaxation by bromophenol blue staining based TAE gel method | Staphylococcus aureus | 41 | ALA4837261 | protein complex format | Scientific Literature | |
5. | ALA4840032 | Binding | Inhibition of Staphylococcus aureus topoisomerase IV decatenation activity using kDNA as substrate by ethidium bromide/bromophenol blue staining based agarose gel electrophoresis analysis | Staphylococcus aureus | 41 | ALA4837261 | protein complex format | Scientific Literature | |
6. | ALA4840033 | Binding | Selectivity index, ratio of IC50 for inhibition of Staphylococcus aureus topoisomerase IV decatenation activity to IC50 for inhibition of Staphylococcus aureus DNA gyrase supercoiling activity | Staphylococcus aureus | 41 | ALA4837261 | assay format | Scientific Literature | |
7. | ALA4840034 | Binding | Inhibition of Staphylococcus aureus DNA Gyrase D83N mutant assessed as reduction in supercoiling pBR322 DNA by measuring relaxation by bromophenol blue staining based TAE gel method | Staphylococcus aureus | 41 | ALA4837261 | assay format | Scientific Literature | |
8. | ALA4840035 | Binding | Selectivity ratio of IC50 for inhibition of Staphylococcus aureus Gyrase D83N mutant to IC50 for inhibition of Staphylococcus aureus Gyrase | Staphylococcus aureus | 21 | ALA4837261 | assay format | Scientific Literature | |
9. | ALA4840036 | Functional | Antibacterial activity against Staphylococcus aureus 3527 by CLSI method | Staphylococcus aureus | 41 | ALA4837261 | organism-based format | Scientific Literature | |
10. | ALA4840037 | Functional | Antibacterial activity against Staphylococcus aureus harbouring GyrA D83N mutant by CLSI method | Staphylococcus aureus | 41 | ALA4837261 | organism-based format | Scientific Literature | |
11. | ALA4840039 | Functional | Growth inhibition of human K/VP.5 cells incubated for 48 hrs by NBTI cell counting analysis | Homo sapiens | 38 | ALA4837261 | tissue-based format | Scientific Literature | |
12. | ALA4840040 | Functional | Antibacterial activity against Streptococcus pyogenes isolates by CLSI method | Streptococcus pyogenes | 2 | ALA4837261 | organism-based format | Scientific Literature | |
13. | ALA4840041 | Functional | Antibacterial activity against Klebsiella pneumoniae isolates by CLSI method | Klebsiella pneumoniae | 2 | ALA4837261 | organism-based format | Scientific Literature | |
14. | ALA4840042 | Functional | Antibacterial activity against Enterobacter cloacae isolates by CLSI method | Enterobacter cloacae | 2 | ALA4837261 | organism-based format | Scientific Literature | |
15. | ALA4840043 | Functional | Antibacterial activity against Escherichia coli isolates by CLSI method | Escherichia coli | 2 | ALA4837261 | organism-based format | Scientific Literature | |
16. | ALA4840044 | Functional | Antibacterial activity against Pseudomonas aeruginosa isolates by CLSI method | Pseudomonas aeruginosa | 2 | ALA4837261 | organism-based format | Scientific Literature | |
17. | ALA4840045 | Functional | Antibacterial activity against vancomycin-resistant Enterococcus faecium by CLSI method | Enterococcus faecium | 1 | ALA4837261 | organism-based format | Scientific Literature | |
18. | ALA4840046 | Functional | Antibacterial activity against vancomycin-resistant Enterococcus faecalis by CLSI method | Enterococcus faecalis | 1 | ALA4837261 | organism-based format | Scientific Literature | |
19. | ALA4840047 | Binding | Inhibition of Staphylococcus aureus DNA Gyrase assessed as reduction in supercoiling pBR322 DNA by measuring induction of single strand breaks by ethidium bromide staining based agarose gel electrophoresis | Staphylococcus aureus | 1 | ALA4837261 | protein complex format | Scientific Literature | |
20. | ALA4840048 | Binding | Inhibition of Staphylococcus aureus DNA Gyrase assessed as reduction in supercoiling pBR322 DNA by measuring induction of double strand breaks by ethidium bromide staining based agarose gel electrophoresis | Staphylococcus aureus | 1 | ALA4837261 | protein complex format | Scientific Literature |