| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4808462 | Functional | Antimalarial activity against Plasmodium falciparum 3D7 infected in human red blood cells after 72 hrs by DAPI-staining based assay | Plasmodium falciparum | 32 | ALA4808169 | organism-based format | Scientific Literature | |
| 2. | ALA4808463 | Physicochemical | Kinetic solubility of compound at pH 2 by nephelometry | 6 | ALA4808169 | small-molecule physicochemical format | Scientific Literature | ||
| 3. | ALA4808464 | Physicochemical | Kinetic solubility of compound at pH 6.5 by nephelometry | 6 | ALA4808169 | small-molecule physicochemical format | Scientific Literature | ||
| 4. | ALA4808465 | ADME | Intrinsic clearance in human liver microsomes assessed per mg of protein in presence of NADPH by UPLC-MS analysis | Homo sapiens | 6 | ALA4808169 | microsome format | Scientific Literature | |
| 5. | ALA4808466 | ADME | Intrinsic clearance in mouse liver microsomes in presence of NADPH by UPLC-MS analysis | Mus musculus | 6 | ALA4808169 | microsome format | Scientific Literature | |
| 6. | ALA4808467 | ADME | Half life in human liver microsomes in presence of NADPH by UPLC-MS analysis | Homo sapiens | 6 | ALA4808169 | microsome format | Scientific Literature | |
| 7. | ALA4808468 | ADME | Half life in mouse liver microsomes in presence of NADPH by UPLC-MS analysis | Mus musculus | 6 | ALA4808169 | microsome format | Scientific Literature | |
| 8. | ALA4808469 | ADME | Intrinsic clearance in human hepatocytes assessed per million cells by UPLC-MS analysis | Homo sapiens | 1 | ALA4808169 | cell-based format | Scientific Literature | |
| 9. | ALA4808470 | ADME | Intrinsic clearance in rat hepatocytes assessed per million cells by UPLC-MS analysis | Rattus norvegicus | 1 | ALA4808169 | cell-based format | Scientific Literature | |
| 10. | ALA4808471 | ADME | Intrinsic clearance in mouse hepatocytes assessed per million cells by UPLC-MS analysis | Mus musculus | 1 | ALA4808169 | cell-based format | Scientific Literature | |
| 11. | ALA4808472 | ADME | Protein binding in rat plasma measured after 6 hrs by LC-MS analysis based equilibrium dialysis method | Rattus norvegicus | 1 | ALA4808169 | cell-free format | Scientific Literature | |
| 12. | ALA4808473 | ADME | Ratio of drug level in blood to plasma in Sprague-Dawley rat at 3 mg/kg, iv administered as infusion for 10 mins measured after 1 hr by LC-MS analysis | Rattus norvegicus | 1 | ALA4808169 | organism-based format | Scientific Literature | |
| 13. | ALA4808474 | ADME | Apparent permeability across apical to basolateral side in human Caco2 cells measured over 120 mins by LC-MS analysis | Homo sapiens | 1 | ALA4808169 | cell-based format | Scientific Literature | |
| 14. | ALA4808475 | ADME | Apparent permeability across basolateral side to apical side in human Caco2 cells measured over 120 mins by LC-MS analysis | Homo sapiens | 1 | ALA4808169 | cell-based format | Scientific Literature | |
| 15. | ALA4808476 | ADME | Efflux ratio of apparent permeability in human Caco2 cells measured over 120 mins by LC-MS analysis | Homo sapiens | 1 | ALA4808169 | cell-based format | Scientific Literature | |
| 16. | ALA4808477 | ADME | Inhibition of CYP1A2 in human liver microsomes assessed as reduction in midazolam 1-hydroxylase activity by . high-pressure liquid chromatography-tandem mass spectrometry | Homo sapiens | 1 | ALA4808169 | microsome format | Scientific Literature | |
| 17. | ALA4808478 | ADME | Inhibition of CYP2C9 in human liver microsomes assessed as reduction in midazolam 1-hydroxylase activity by . high-pressure liquid chromatography-tandem mass spectrometry | Homo sapiens | 1 | ALA4808169 | microsome format | Scientific Literature | |
| 18. | ALA4808479 | ADME | Inhibition of CYP2C19 in human liver microsomes assessed as reduction in midazolam 1-hydroxylase activity by . high-pressure liquid chromatography-tandem mass spectrometry | Homo sapiens | 1 | ALA4808169 | microsome format | Scientific Literature | |
| 19. | ALA4808480 | ADME | Inhibition of CYP2D6 in human liver microsomes assessed as reduction in midazolam 1-hydroxylase activity by . high-pressure liquid chromatography-tandem mass spectrometry | Homo sapiens | 1 | ALA4808169 | microsome format | Scientific Literature | |
| 20. | ALA4808481 | ADME | Inhibition of CYP3A4 in human liver microsomes assessed as reduction in midazolam 1-hydroxylase activity by . high-pressure liquid chromatography-tandem mass spectrometry | Homo sapiens | 1 | ALA4808169 | microsome format | Scientific Literature |
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