# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4835172 | B | Inhibition of human recombinant ADAMTS-5 assessed as cleavage of fluorescent substrate using FAM-TBIS-1 by biochemical assay | Homo sapiens | 60 | ALA4834410 | single protein format | Scientific Literature | |
2. | ALA4835174 | B | Inhibition of human recombinant ADAMTS-1 (AA253 to 734) assessed as cleavage of fluorescent substrate using 5(6)-fluorescein-NH-AELQGRPISIAK-5(6)-TAMRA as substrate incubated for 120 mins by biochemical assay | Homo sapiens | 15 | ALA4834410 | single protein format | Scientific Literature | |
3. | ALA4835175 | B | Inhibition of human recombinant ADAMTS-4 (AA1 to 520) assessed as cleavage of fluorescent substrate using as TBIS-1 substrate incubated for 180 mins by biochemical assay | Homo sapiens | 14 | ALA4834410 | single protein format | Scientific Literature | |
4. | ALA4835176 | B | Inhibition of human recombinant MMP2 (AA34 to 660) assessed as cleavage of fluorescent substrate using 390 MMP FRET as substrate incubated for 30 mins by biochemical assay | Homo sapiens | 14 | ALA4834410 | single protein format | Scientific Literature | |
5. | ALA4835177 | B | Inhibition of human recombinant MMP14 (AA112 to 298) assessed as cleavage of fluorescent substrate using 390 MMP FRET as substrate incubated for 30 mins by biochemical assay | Homo sapiens | 3 | ALA4834410 | single protein format | Scientific Literature | |
6. | ALA4835178 | B | Inhibition of human recombinant TACE (AA34 to 660) assessed as cleavage of fluorescent substrate using 5FAM-LAQAVRSSSRK-5TAMRA as substrate by biochemical assay | Homo sapiens | 14 | ALA4834410 | single protein format | Scientific Literature | |
7. | ALA4835179 | B | Inhibition of ADAM-9 (unknown origin) | Homo sapiens | 2 | ALA4834410 | single protein format | Scientific Literature | |
8. | ALA4835180 | B | Inhibition of ADAM-10 (unknown origin) | Homo sapiens | 2 | ALA4834410 | single protein format | Scientific Literature | |
9. | ALA4835181 | B | Inhibition of Caspase 3 (unknown origin) | Homo sapiens | 2 | ALA4834410 | single protein format | Scientific Literature | |
10. | ALA4835182 | B | Inhibition of Cathepsin D (unknown origin) | Homo sapiens | 2 | ALA4834410 | single protein format | Scientific Literature | |
11. | ALA4835183 | B | Inhibition of DPP-IV (unknown origin) | Homo sapiens | 2 | ALA4834410 | single protein format | Scientific Literature | |
12. | ALA4835184 | B | Inhibition of MMP-1 (unknown origin) | Homo sapiens | 2 | ALA4834410 | single protein format | Scientific Literature | |
13. | ALA4835185 | B | Inhibition of MMP-3 (unknown origin) | Homo sapiens | 2 | ALA4834410 | single protein format | Scientific Literature | |
14. | ALA4835186 | B | Inhibition of MMP-7 (unknown origin) | Homo sapiens | 2 | ALA4834410 | single protein format | Scientific Literature | |
15. | ALA4835187 | B | Inhibition of MMP-8 (unknown origin) | Homo sapiens | 2 | ALA4834410 | single protein format | Scientific Literature | |
16. | ALA4835188 | B | Inhibition of MMP-9 (unknown origin) | Homo sapiens | 2 | ALA4834410 | single protein format | Scientific Literature | |
17. | ALA4835189 | B | Inhibition of MMP-13 (unknown origin) | Homo sapiens | 2 | ALA4834410 | single protein format | Scientific Literature | |
18. | ALA4835190 | B | Inhibition of MMP-12 (unknown origin) | Homo sapiens | 2 | ALA4834410 | single protein format | Scientific Literature |