| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4819906 | B | Inhibition of CDK9/cyclin T (unknown origin) using YSPTSPSYSPTSPSYSPTSPKKK or histone H1 as substrate incubated for 2 hrs in presence of [gamma-33P]ATP by radioactive filter binding assay | Homo sapiens | 16 | protein complex format | Scientific Literature | ||
| 2. | ALA4819907 | F | Antiproliferative activity against human MV4-11 cells incubated for 72 hrs by MTT assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 3. | ALA4819908 | F | Antiproliferative activity against human MOLM-13 cells incubated for 72 hrs by MTT assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 4. | ALA4819909 | F | Antiproliferative activity against human HCT-116 cells incubated for 72 hrs by MTT assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 5. | ALA4819910 | F | Antiproliferative activity against mouse B16 cells incubated for 72 hrs by MTT assay | Mus musculus | 16 | cell-based format | Scientific Literature | ||
| 6. | ALA4819911 | F | Antiproliferative activity against human A549 cells incubated for 72 hrs by MTT assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 7. | ALA4819912 | F | Antiproliferative activity against human HepG2 cells incubated for 72 hrs by MTT assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 8. | ALA4819913 | F | Antiproliferative activity against human MCF7 cells incubated for 72 hrs by MTT assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 9. | ALA4819914 | B | Protac activity at CRBN/CDK9 in human MV4-11 cells assessed as CDK9 degradation rate at 500 nM incubated for 6 hrs by Western blot assay relative to control | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 10. | ALA4819915 | B | Protac activity at CRBN/CDK9 in human MOLM-13 cells assessed as CDK9 degradation rate at 500 nM incubated for 6 hrs by Western blot assay relative to control | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 11. | ALA4819916 | B | Protac activity at CRBN/CDK9 in human MV4-11 cells assessed as induction of CDK9 degradation incubated for 6 hrs by Western blot assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 12. | ALA4819917 | B | Protac activity at CRBN/CDK9 in human MV4-11 cells assessed as induction of CDK9 degradation by measuring downregulation of CDK9 expression level at 250 nM by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4819918 | B | Protac activity at CRBN/CDK9 in human MV4-11 cells assessed as induction of CDK9 degradation by measuring downregulation of MCL-1 protein expression level at 250 nM by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4819919 | F | Induction of apoptosis in human MV4-11 cells cells assessed as total apoptotic cells at 1 nM after 6 hrs by AnnexinV-FITC/propidium iodide staining based flow cytometry (Rvb = 9.75 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4819920 | F | Induction of apoptosis in human MV4-11 cells cells assessed as total apoptotic cells at 30 nM after 6 hrs by AnnexinV-FITC/propidium iodide staining based flow cytometry (Rvb = 9.75 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4819921 | F | Induction of apoptosis in human MV4-11 cells cells assessed as total apoptotic cells at 100 nM after 6 hrs by AnnexinV-FITC/propidium iodide staining based flow cytometry (Rvb = 9.75 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4819922 | F | Induction of apoptosis in human MV4-11 cells cells assessed as total apoptotic cells at 250 nM after 6 hrs by AnnexinV-FITC/propidium iodide staining based flow cytometry (Rvb = 9.75 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4819923 | F | Induction of apoptosis in human MV4-11 cells cells assessed as total apoptotic cells at 500 nM after 6 hrs by AnnexinV-FITC/propidium iodide staining based flow cytometry (Rvb = 9.75 %) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 19. | ALA4819924 | F | Induction of apoptosis in human MV4-11 cells cells assessed as total apoptotic cells at 1000 nM after 6 hrs by AnnexinV-FITC/propidium iodide staining based flow cytometry (Rvb = 9.75 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4819925 | F | Induction of apoptosis in human MV4-11 cells cells assessed as viable cells at 1 nM after 6 hrs by AnnexinV-FITC/propidium iodide staining based flow cytometry (Rvb = 90.1 %) | Homo sapiens | 1 | cell-based format | Scientific Literature |
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