# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4817244 | B | Inhibition of human CA1 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assay | Homo sapiens | 21 | single protein format | Scientific Literature | ||
2. | ALA4817245 | B | Inhibition of human CA2 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assay | Homo sapiens | 21 | single protein format | Scientific Literature | ||
3. | ALA4817246 | B | Inhibition of human CA9 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assay | Homo sapiens | 23 | single protein format | Scientific Literature | ||
4. | ALA4817247 | B | Selectivity index, ratio of Ki for inhibition of human CA1 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assay to Ki for inhibition of human CA9 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assay | Homo sapiens | 21 | assay format | Scientific Literature | ||
5. | ALA4817248 | B | Selectivity index, ratio of Ki for inhibition of human CA2 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assay to Ki for inhibition of human CA9 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assay | Homo sapiens | 21 | assay format | Scientific Literature | ||
6. | ALA4817249 | F | Cytotoxicity against human HSC-2 cells incubated for 48 hrs by MTT assay | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
7. | ALA4817250 | A | Cytotoxicity against human HGF cells incubated for 48 hrs by MTT assay | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
8. | ALA4817251 | U | Selectivity index, ratio of CC50 for human HSC-2 cells to CC50 for human HGF | Homo sapiens | 23 | assay format | Scientific Literature | ||
9. | ALA4817252 | F | Induction of apoptosis in human HSC-2 cells assessed as increase in cleaved PARP level at 3 to 100 uM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
10. | ALA4817253 | F | Induction of apoptosis in human HSC-2 cells assessed as increase in cleaved caspase 3 level at 3 to 100 uM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |