| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4827171 | B | Inhibition of recombinant human N-terminal GST-tagged NSD2 CD (941 to 1240 residues) expressed in Escherichia coli using SAM as substrate in presence of nucleosomes by AlphaLISA method | Homo sapiens | 38 | ALA4825702 | assay format | Scientific Literature | |
| 2. | ALA4827172 | B | Inhibition of NSD2 E1009K mutant (unknown origin) using SAM as substrate preincubated for 10 mins followed by substrate addition measured after 4 hrs by AlphaLISA method | Homo sapiens | 1 | ALA4825702 | single protein format | Scientific Literature | |
| 3. | ALA4827173 | B | Inhibition of NSD1 (unknown origin) using SAM as substrate preincubated for 10 mins followed by substrate addition measured after 4 hrs by AlphaLISA method | Homo sapiens | 1 | ALA4825702 | single protein format | Scientific Literature | |
| 4. | ALA4827174 | B | Inhibition of SETD2 (unknown origin) using SAM as substrate preincubated for 10 mins followed by substrate addition measured after 4 hrs by AlphaLISA method | Homo sapiens | 1 | ALA4825702 | single protein format | Scientific Literature | |
| 5. | ALA4827175 | B | Inhibition of EZH2 (unknown origin) using SAM as substrate preincubated for 10 mins followed by substrate addition measured after 4 hrs by HTRF method | Homo sapiens | 1 | ALA4825702 | single protein format | Scientific Literature | |
| 6. | ALA4827176 | B | Inhibition of MLLI (unknown origin) using SAM as substrate preincubated for 10 mins followed by substrate addition measured after 4 hrs by HTRF method | Homo sapiens | 1 | ALA4825702 | single protein format | Scientific Literature | |
| 7. | ALA4827177 | B | Inhibition of MLL4 (unknown origin) using SAM as substrate preincubated for 10 mins followed by substrate addition measured after 4 hrs by HTRF method | Homo sapiens | 1 | ALA4825702 | single protein format | Scientific Literature | |
| 8. | ALA4827178 | B | Inhibition of DOT1L (unknown origin) using SAM as substrate preincubated for 10 mins followed by substrate addition measured after 4 hrs by AlphaLISA method | Homo sapiens | 1 | ALA4825702 | single protein format | Scientific Literature | |
| 9. | ALA4827179 | B | Inhibition of PRMT4 (unknown origin) using SAM as substrate preincubated for 10 mins followed by substrate addition measured after 4 hrs by AlphaLISA method | Homo sapiens | 1 | ALA4825702 | single protein format | Scientific Literature | |
| 10. | ALA4827180 | B | Inhibition of PRMT5 (unknown origin) using SAM as substrate preincubated for 10 mins followed by substrate addition measured after 4 hrs by AlphaLISA method | Homo sapiens | 1 | ALA4825702 | single protein format | Scientific Literature | |
| 11. | ALA4827181 | B | Inhibition of human NSD2 in human RS4-11 cells assessed as suppression of H3K36me2 measured up to 96 hrs by Western blot analysis | Homo sapiens | 1 | ALA4825702 | cell-based format | Scientific Literature | |
| 12. | ALA4827182 | B | Inhibition of human NSD2 in human MV4-11 cells assessed as suppression of H3K36me2 measured up to 96 hrs by Western blot analysis | Homo sapiens | 1 | ALA4825702 | cell-based format | Scientific Literature | |
| 13. | ALA4827183 | B | Inhibition of human NSD2 in human KMS-11 cells assessed as suppression of H3K36me2 measured up to 96 hrs by Western blot analysis | Homo sapiens | 1 | ALA4825702 | cell-based format | Scientific Literature | |
| 14. | ALA4827184 | B | Inhibition of human NSD2 in human OPM-2 cells assessed as suppression of H3K36me2 measured up to 96 hrs by Western blot analysis | Homo sapiens | 1 | ALA4825702 | cell-based format | Scientific Literature | |
| 15. | ALA4827185 | B | Inhibition of human NSD2 in human RS4-11 cells assessed as effect on total histone H3 level at 5 to 50 uM measured after 4 days by Western blot analysis | Homo sapiens | 1 | ALA4825702 | cell-based format | Scientific Literature | |
| 16. | ALA4827186 | B | Inhibition of human NSD2 in human MV4-11 cells assessed as effect on total histone H3 level at 5 to 50 uM measured after 4 days by Western blot analysis | Homo sapiens | 1 | ALA4825702 | cell-based format | Scientific Literature | |
| 17. | ALA4827187 | B | Inhibition of human NSD2 in human KMS-11 cells assessed as effect on total histone H3 level at 5 to 50 uM measured after 4 days by Western blot analysis | Homo sapiens | 1 | ALA4825702 | cell-based format | Scientific Literature | |
| 18. | ALA4827188 | B | Inhibition of human NSD2 in human OPM-2 cells assessed as effect on total histone H3 level at 5 to 50 uM measured after 4 days by Western blot analysis | Homo sapiens | 1 | ALA4825702 | cell-based format | Scientific Literature | |
| 19. | ALA4827189 | F | Antiproliferative activity against human RS4-11 cells assessed as reduction in cell viability incubated for 24 hrs by CCK8 assay | Homo sapiens | 1 | ALA4825702 | cell-based format | Scientific Literature | |
| 20. | ALA4827190 | F | Antiproliferative activity against human KMS-11 cells assessed as reduction in cell viability incubated for 24 hrs by CCK8 assay | Homo sapiens | 1 | ALA4825702 | cell-based format | Scientific Literature |
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