# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4807193 | F | Inhibition of GPR174 (unknown origin) in cells assessed as incorporation of nuclear localization sequence into transmembrane protein by cellular redistribution assay | Homo sapiens | 26 | assay format | Patent Bioactivity Data | ||
2. | ALA4807197 | F | Antagonist activity at human GPR174 expressed in cells assessed as inhibition of CRE-luc reporter activity by measuring decrease in Gs-protein signalling activity relative to control | Homo sapiens | 7 | cell-based format | Patent Bioactivity Data | ||
3. | ALA4807198 | F | Allosteric modulator activity at human GPR174 expressed in cells assessed as inhibition of CRE-luc reporter activity by measuring decrease in Gs-protein signalling activity relative to control | Homo sapiens | 6 | cell-based format | Patent Bioactivity Data | ||
4. | ALA4807261 | F | Antagonist activity at GPR174 (unknown origin) expressed in HEK293 cells assessed as inhibition of PS-induced GPR174 signaling incubated for 15 mins by GloSensor assay | Homo sapiens | 7 | cell-based format | Patent Bioactivity Data | ||
5. | ALA4807280 | F | Antagonist activity at human GPR174 by CRA | Homo sapiens | 7 | assay format | Patent Bioactivity Data | ||
6. | ALA4807281 | B | Allosteric modulator activity at human GPR174 by CRA | Homo sapiens | 7 | single protein format | Patent Bioactivity Data | ||
7. | ALA4807312 | F | Induction of INF-gamma production in anti-CD3/CD28-stimulated human PBMCs assessed as fold increase in INF-gamma level at 10 uM after 24 hrs by ELISA | Homo sapiens | 1 | tissue-based format | Patent Bioactivity Data | ||
8. | ALA4807313 | F | Induction of INF-gamma production in anti-CD3/CD28-stimulated human PBMCs assessed as fold increase in INF-gamma level at 3 uM after 24 hrs by ELISA | Homo sapiens | 1 | tissue-based format | Patent Bioactivity Data | ||
9. | ALA4807316 | F | Induction of INF-gamma production in anti-CD3/CD28-stimulated human PBMCs assessed as fold increase in INF-gamma level at 10 uM after 24 hrs in presence of 0.1 uM A2aR inhibitor ZM-241385 by ELISA | Homo sapiens | 1 | tissue-based format | Patent Bioactivity Data | ||
10. | ALA4807317 | F | Induction of INF-gamma production in anti-CD3/CD28-stimulated human PBMCs assessed as fold increase in INF-gamma level at 3 uM after 24 hrs in presence of 0.1 uM A2aR inhibitor ZM-241385 by ELISA | Homo sapiens | 1 | tissue-based format | Patent Bioactivity Data | ||
11. | ALA4807320 | F | Induction of IL-2 production in anti-CD3/CD28-stimulated human PBMCs assessed as fold increase in IL-2 level at 10 uM after 24 hrs by ELISA | Homo sapiens | 1 | tissue-based format | Patent Bioactivity Data | ||
12. | ALA4807321 | F | Induction of IL-2 production in anti-CD3/CD28-stimulated human PBMCs assessed as fold increase in IL-2 level at 3 uM after 24 hrs by ELISA | Homo sapiens | 1 | tissue-based format | Patent Bioactivity Data | ||
13. | ALA4807324 | F | Induction of IL-2 production in anti-CD3/CD28-stimulated human PBMCs assessed as fold increase in IL-2 level at 10 uM after 24 hrs 0.1 uM in presence of A2aR inhibitor ZM-241385 by ELISA | Homo sapiens | 1 | tissue-based format | Patent Bioactivity Data | ||
14. | ALA4807325 | F | Induction of IL-2 production in anti-CD3/CD28-stimulated human PBMCs assessed as fold increase in IL-2 level at 3 uM after 24 hrs in presence of 0.1 uM of A2aR inhibitor ZM-241385 by ELISA | Homo sapiens | 1 | tissue-based format | Patent Bioactivity Data | ||
15. | ALA4807328 | F | Induction of TNF production in anti-CD3/CD28-stimulated human PBMCs assessed as fold increase in TNF level at 10 uM after 24 hrs by ELISA | Homo sapiens | 1 | tissue-based format | Patent Bioactivity Data | ||
16. | ALA4807329 | F | Induction of TNF production in anti-CD3/CD28-stimulated human PBMCs assessed as fold increase in TNF level at 3 uM after 24 hrs by ELISA | Homo sapiens | 1 | tissue-based format | Patent Bioactivity Data | ||
17. | ALA4807332 | F | Induction of TNF production in anti-CD3/CD28-stimulated human PBMCs assessed as fold increase in TNF level at 10 uM after 24 hrs in presence of 0.1 uM of A2aR inhibitor ZM-241385 by ELISA | Homo sapiens | 1 | tissue-based format | Patent Bioactivity Data | ||
18. | ALA4807333 | F | Induction of TNF production in anti-CD3/CD28-stimulated human PBMCs assessed as fold increase in TNF level at 3 uM after 24 hrs in presence of 0.1 uM of A2aR inhibitor ZM-241385 by ELISA | Homo sapiens | 1 | tissue-based format | Patent Bioactivity Data | ||
19. | ALA4807337 | F | Induction of GM-CSF production in anti-CD3/CD28-stimulated human PBMCs assessed as fold increase in GM-CSF level at 10 uM after 24 hrs by ELISA | Homo sapiens | 1 | tissue-based format | Patent Bioactivity Data | ||
20. | ALA4807338 | F | Induction of GM-CSF production in anti-CD3/CD28-stimulated human PBMCs assessed as fold increase in GM-CSF level at 3 uM after 24 hrs by ELISA | Homo sapiens | 1 | tissue-based format | Patent Bioactivity Data |