# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4808118 | F | Antagonist activity at human MRGPRX4 expressed in HEK cells incubated in dark for 1 hr at 37 degree C and then incubated for 30 mins at room temperature in presence of 10 pM of bilirubin by HTRF assay | Homo sapiens | 309 | cell-based format | Patent Bioactivity Data | ||
2. | ALA4808119 | F | Antagonist activity at human MRGPRX4 expressed in HEK cells incubated in dark for 1 hr at 37 degree C and then incubated for 30 mins at room temperature in presence of 10 uM of bilirubin by HTRF assay | Homo sapiens | 17 | cell-based format | Patent Bioactivity Data | ||
3. | ALA4808120 | F | Antagonist activity at human MRGPRX4 expressed in HEK cells incubated in dark for 1 hr at 37 degree C and then incubated for 30 mins at room temperature in presence of 100 uM of conjugated bilirubin by HTRF assay | Homo sapiens | 17 | cell-based format | Patent Bioactivity Data | ||
4. | ALA4808121 | F | Antagonist activity at human MRGPRX4 expressed in HEK cells incubated in dark for 1 hr at 37 degree C and then incubated for 30 mins at room temperature in presence of 20 uM of deoxycholic acid by HTRF assay | Homo sapiens | 17 | cell-based format | Patent Bioactivity Data | ||
5. | ALA4808122 | F | Antagonist activity at human MRGPRX4 expressed in HEK cells incubated in dark for 1 hr at 37 degree C and then incubated for 30 mins at room temperature in presence of 50 uM of urobilin by HTRF assay | Homo sapiens | 17 | cell-based format | Patent Bioactivity Data | ||
6. | ALA4808123 | F | Antagonist activity at human MRGPRX4 expressed in HEK cells incubated in dark for 1 hr at 37 degree C and then incubated for 30 mins at room temperature in presence of 50 uM of obeticholic acid by HTRF assay | Homo sapiens | 17 | cell-based format | Patent Bioactivity Data | ||
7. | ALA4808124 | A | Cmax in C57BL/6 mouse at 50 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 13 | organism-based format | Patent Bioactivity Data | ||
8. | ALA4808125 | A | AUC in C57BL/6 mouse at 50 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 13 | organism-based format | Patent Bioactivity Data | ||
9. | ALA4808126 | A | Half life in C57BL/6 mouse at 50 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 13 | organism-based format | Patent Bioactivity Data | ||
10. | ALA4808127 | F | Antagonist activity at human MRGPRX4 expressed in HEK cells incubated in dark for 1 hr at 37 degree C and then incubated for 30 mins at room temperature in presence of 10 uM of BAR-502 by HTRF assay | Homo sapiens | 8 | cell-based format | Patent Bioactivity Data |