| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4824597 | A | Cytotoxicity against mouse BV-2 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay | Mus musculus | 10 | ALA4823279 | cell-based format | Scientific Literature | |
| 2. | ALA4824598 | F | Anti-neuroinflammatory activity in mouse BV-2 cells assessed as inhibition of LPS-induced NO production measured after 24 hrs by Griess reagent based assay | Mus musculus | 10 | ALA4823279 | cell-based format | Scientific Literature | |
| 3. | ALA4824599 | F | Anti-neuroinflammatory activity against LPS stimulated mouse BV-2 cells assessed as reduction in iNOS protein expression measured after 24 hrs in presence of LPS by western blot analysis | Mus musculus | 1 | ALA4823279 | cell-based format | Scientific Literature | |
| 4. | ALA4824600 | F | Anti-neuroinflammatory activity against LPS stimulated mouse BV-2 cells assessed as reduction in COX-2 protein expression at 1 to 10 uM measured after 24 hrs in presence of LPS by western blot analysis | Mus musculus | 1 | ALA4823279 | cell-based format | Scientific Literature | |
| 5. | ALA4824601 | F | Inhibition of TLR4 production in LPS stimulated mouse BV-2 cells at 1 to 10 uM preincubated with LPS for 1 hr followed by incubation with compound for 16 hrs by western blot analysis | Mus musculus | 1 | ALA4823279 | tissue-based format | Scientific Literature | |
| 6. | ALA4824602 | B | Inhibition of JNK phosphorylation in LPS stimulated mouse BV-2 cells at 1 to 10 uM preincubated with LPS for 1 hr followed by incubation with compound for 16 hrs by western blot analysis | Mus musculus | 1 | ALA4823279 | tissue-based format | Scientific Literature | |
| 7. | ALA4824603 | B | Inhibition of ERK phosphorylation in LPS stimulated mouse BV-2 cells at 1 to 10 uM preincubated with LPS for 1 hr followed by incubation with compound for 16 hrs by western blot analysis | Mus musculus | 1 | ALA4823279 | tissue-based format | Scientific Literature | |
| 8. | ALA4824604 | B | Inhibition of p38 phosphorylation in LPS stimulated mouse BV-2 cells at 1 to 10 uM preincubated with LPS for 1 hr followed by incubation with compound for 16 hrs by western blot analysis | Mus musculus | 1 | ALA4823279 | tissue-based format | Scientific Literature | |
| 9. | ALA4824605 | B | Inhibition of NF-kappaB p65 nuclear translocation in LPS-stimulated mouse BV-2 cells at 10 uM incubated with compound prior to LPS stimulation by DAPI staining based immunofluorescence assay | Mus musculus | 1 | ALA4823279 | tissue-based format | Scientific Literature | |
| 10. | ALA4824606 | F | Anti-neuroinflammatory activity in mouse BV-2 cells assessed as reduction in LPS-stimulated IL-1 beta production at 1 to 10 uM preincubated for 1 hr followed by LPS treatment and measured after 24 hrs by ELISA | Mus musculus | 1 | ALA4823279 | cell-based format | Scientific Literature | |
| 11. | ALA4824607 | F | Anti-neuroinflammatory activity in mouse BV-2 cells assessed as reduction in LPS-stimulated IL-6 production at 1 to 10 uM preincubated for 1 hr followed by LPS treatment and measured after 24 hrs by ELISA | Mus musculus | 1 | ALA4823279 | cell-based format | Scientific Literature | |
| 12. | ALA4824608 | F | Anti-neuroinflammatory activity in mouse BV-2 cells assessed as reduction in LPS-stimulated TNFalpha production at 1 to 10 uM preincubated for 1 hr followed by LPS treatment and measured after 24 hrs by ELISA | Mus musculus | 1 | ALA4823279 | cell-based format | Scientific Literature | |
| 13. | ALA4824609 | F | Anti-neuroinflammatory activity in mouse BV-2 cells assessed as reduction in LPS-stimulated iNOS mRNA expression at 1 to 10 uM by qRT-PCR analysis | Mus musculus | 1 | ALA4823279 | cell-based format | Scientific Literature | |
| 14. | ALA4824610 | F | Anti-neuroinflammatory activity in mouse BV-2 cells assessed as reduction in LPS-stimulated COX-2 mRNA expression at 1 to 10 uM by qRT-PCR analysis | Mus musculus | 1 | ALA4823279 | cell-based format | Scientific Literature | |
| 15. | ALA4824611 | F | Anti-neuroinflammatory activity in mouse BV-2 cells assessed as reduction in LPS-stimulated IL-1beta mRNA expression by qRT-PCR analysis | Mus musculus | 1 | ALA4823279 | cell-based format | Scientific Literature | |
| 16. | ALA4824612 | F | Anti-neuroinflammatory activity in mouse BV-2 cells assessed as reduction in LPS-stimulated IL-6 mRNA expression by qRT-PCR analysis | Mus musculus | 1 | ALA4823279 | cell-based format | Scientific Literature | |
| 17. | ALA4824613 | F | Anti-neuroinflammatory activity in mouse BV-2 cells assessed as reduction in LPS-stimulated TNF-alpha mRNA expression by qRT-PCR analysis | Mus musculus | 1 | ALA4823279 | cell-based format | Scientific Literature |
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