# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4815962 | F | Antitrypanosomal activity against Trypanosoma brucei brucei assessed as parasite growth inhibition | Trypanosoma brucei brucei | 40 | organism-based format | Scientific Literature | ||
2. | ALA4815963 | T | Selectivity index, ratio of EC50 for cytotoxicity against mouse primary macrophage to EC50 for antileishmanial activity against Leishmania infantum MHOM/MA(BE)/67 infected in mouse primary peritoneal macrophages | 22 | assay format | Scientific Literature | |||
3. | ALA4815964 | A | Cytotoxicity against mouse primary macrophage cells assessed as reduction in cell viability | Mus musculus | 39 | cell-based format | Scientific Literature | ||
4. | ALA4815965 | F | Antileishmanial activity against Leishmania infantum MHOM/MA(BE)/67 infected in mouse primary peritoneal macrophages treated 2 hrs post-infection and incubated for 5 days by Giemsa staining based microscopic analysis | Leishmania infantum | 40 | organism-based format | Scientific Literature | ||
5. | ALA4815966 | T | Selectivity index, ratio of EC50 for cytotoxicity against human MRC5 cells to EC50 for antitrypanosomal activity against Trypanosoma cruzi Tulahuen CL2 infected in human MRC5 cells | 26 | cell-based format | Scientific Literature | |||
6. | ALA4815967 | A | Cytotoxicity against human MRC5 cells assessed as reduction in cell viability after 3 days by resazurin dye based fluorimetric analysis | Homo sapiens | 39 | cell-based format | Scientific Literature | ||
7. | ALA4815968 | F | Antitrypanosomal activity against Trypanosoma cruzi Tulahuen CL2 infected in human MRC5 cells assessed as inhibition of parasite growth incubated for 7 days by chlorophenol red-fl-D-galactopyranoside based spectrophotometric analysis | Trypanosoma cruzi | 40 | organism-based format | Scientific Literature | ||
8. | ALA4815970 | F | Antitrypanosomal activity against Trypanosoma brucei rhodesiense assessed as parasite growth inhibition | Trypanosoma brucei rhodesiense | 40 | organism-based format | Scientific Literature | ||
9. | ALA4815971 | T | Selectivity index, ratio of EC50 for human MRC5 cells to EC50 for antitrypanosomal activity against Trypanosoma brucei brucei | 26 | assay format | Scientific Literature | |||
10. | ALA4815972 | T | Selectivity index, ratio of EC50 for human MRC5 cells to EC50 for antitrypanosomal activity against Trypanosoma brucei rhodesiense | 27 | assay format | Scientific Literature | |||
11. | ALA4817117 | F | Antitrypanosomal activity against Trypanosoma brucei brucei by drug sensitivity assay | Trypanosoma brucei brucei | 8 | organism-based format | Scientific Literature | ||
12. | ALA4817118 | F | Antitrypanosomal activity against Trypanosoma brucei gambiense by drug sensitivity assay | Trypanosoma brucei gambiense | 3 | organism-based format | Scientific Literature | ||
13. | ALA4817119 | A | Cytotoxicity against human NHDF cells assessed as reduction in cell viability by XTT assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
14. | ALA4817120 | T | Selective index, ratio of IC50 for human NHDF cells to EC50 for Trypanosoma brucei brucei | 6 | assay format | Scientific Literature | |||
15. | ALA4817121 | T | Selective index, ratio of IC50 for human NHDF cells to EC50 for Trypanosoma brucei gambiense | 3 | assay format | Scientific Literature | |||
16. | ALA4817122 | F | Cytotoxicity against human CCRF-CEM cells assessed as reduction in cell viability by XTT assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
17. | ALA4817123 | F | Cytotoxicity against human HeLa S3 cells assessed as reduction in cell viability by XTT assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
18. | ALA4817124 | F | Cytotoxicity against human HL-60 cells assessed as reduction in cell viability by XTT assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
19. | ALA4817125 | F | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability by XTT assay | Homo sapiens | 8 | cell-based format | Scientific Literature |