#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4843234	Binding	Inhibition of IDO1 in mouse Panc02 cells assessed as reduction in NFK level incubated for 48 hrs by RFMS analysis	Mus musculus	7	ALA4842341	cell-based format	Scientific Literature
2.	ALA4843237	Binding	Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assay	Homo sapiens	62	ALA4842341	cell-based format	Scientific Literature
3.	ALA4843239	ADME	Intrinsic clearance in human liver microsomes at 1 uM measured up to 45 mins in presence of NADPH by LC-MS/MS analysis	Homo sapiens	48	ALA4842341	microsome format	Scientific Literature
4.	ALA4843244	ADME	Clearance in CD-1 mouse at 0.3 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis	Mus musculus	7	ALA4842341	organism-based format	Scientific Literature
5.	ALA4843245	ADME	Volume of distribution at steady state in CD-1 mouse at 0.3 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis	Mus musculus	7	ALA4842341	organism-based format	Scientific Literature
6.	ALA4843246	ADME	Terminal half life in CD-1 mouse at 0.3 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis	Mus musculus	7	ALA4842341	organism-based format	Scientific Literature
7.	ALA4843247	ADME	AUC (0 to infinity) in CD-1 mouse at 0.3 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis	Mus musculus	7	ALA4842341	organism-based format	Scientific Literature
8.	ALA4843248	ADME	Cmax in CD-1 mouse at 10 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis	Mus musculus	7	ALA4842341	organism-based format	Scientific Literature
9.	ALA4843249	ADME	Oral bioavailability in CD-1 mouse at 10 mg/kg measured upto 24 hrs by LC-MS/MS analysis	Mus musculus	7	ALA4842341	organism-based format	Scientific Literature
10.	ALA4843250	Binding	Inhibition of human ERG by fluorescence polarization assay	Homo sapiens	6	ALA4842341	single protein format	Scientific Literature
11.	ALA4843253	Binding	Inhibition of human ERG by manual patch clamp method	Homo sapiens	4	ALA4842341	assay format	Scientific Literature
12.	ALA4843254	Binding	Selectivity ratio of IC50 for inhibition of human ERG by manual patch clamp method to IC50 for inhibition of IDO1 in human HeLa cells	Homo sapiens	10	ALA4842341	cell-based format	Scientific Literature
13.	ALA4843262	ADME	Drug concentration in tumor of NSG mouse xenografted with human SKOV3 cells at 125 mg/kg, po QD administered for 5 days and measured 24 hrs post dose	Mus musculus	8	ALA4842341	organism-based format	Scientific Literature
14.	ALA4843276	ADME	Protein binding in human plasma at 5 uM incubated for 5 hrs by rapid equilibrium dialysis	Homo sapiens	45	ALA4842341	cell-free format	Scientific Literature
15.	ALA4843280	ADME	Inhibition of CYP2C9 in human liver microsomes using sulfaphenazole as substrate incubated for 10 mins in presence of NADPH by LCMS/MS analysis	Homo sapiens	27	ALA4842341	microsome format	Scientific Literature
16.	ALA4843297	ADME	Drug concentration in plasma of NSG mouse xenografted with human SKOV3 cells at 125 mg/kg, po QD administered for 5 days and measured 24 hrs post dose	Mus musculus	8	ALA4842341	organism-based format	Scientific Literature
17.	ALA4843301	ADME	Protein binding in mouse plasma at 5 uM incubated for 5 hrs by rapid equilibrium dialysis based LC-MS/MS analysis	Mus musculus	13	ALA4842341	cell-free format	Scientific Literature
18.	ALA4843303	Functional	In vivo inhibition of IDO1 in tumor of NSG mouse xenografted with human SKOV3 cells assessed as KYN level at 125 mg/kg, po QD administered for 5 days and measured 24 hrs post dose	Mus musculus	8	ALA4842341	organism-based format	Scientific Literature
19.	ALA4843307	Binding	Inhibition of IDO1 in human whole blood stimulated with IFNgamma/LPS using L-tryptophan/kynurenine as substrate incubated for 15 mins followed by IFNgamma/LPS stimulation and incubated for 24 hrs by LC-MS analysis	Homo sapiens	4	ALA4842341	tissue-based format	Scientific Literature
20.	ALA4843308	Functional	In vivo inhibition of IDO1 in tumor of po dosed NSG mouse xenografted with human SKOV3 cells assessed as reduction in KYN level administered twice daily for 5 days measured at 12 hrs post dose	Mus musculus	1	ALA4842341	organism-based format	Scientific Literature