# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4845553 | F | Antiviral activity against Influenza A virus (A/WSN/1933(H1N1)) infected in MDCK cells assessed as s reduction in virus-induced cytopathic effect after 40 hrs incubation by CellTiter-Glo assay | Influenza A virus | 14 | organism-based format | Scientific Literature | ||
2. | ALA4845554 | A | Cytotoxicity against MDCK cells assessed as reduction in cell viability by CellTiter-Glo assay | Canis lupus familiaris | 14 | cell-based format | Scientific Literature | ||
3. | ALA4845555 | T | Selectivity ratio of CC50 for MDCK cells to IC50 for Influenza A virus A/WSN/33(H1N1) infected in MDCK cells | 13 | cell-based format | Scientific Literature | |||
4. | ALA4845556 | F | Antiviral activity against Influenza A virus (A/WSN/1933(H1N1)) infected in MDCK cells assessed as suppression of M2 protein expression at early stage of infection measured after 2 hrs post infection by Western blot analysis | Influenza A virus | 1 | organism-based format | Scientific Literature | ||
5. | ALA4845557 | F | Antiviral activity against Influenza A virus (A/WSN/1933(H1N1)) infected in MDCK cells assessed as suppression of NP protein expression measured after 2 hrs post infection by Western blot analysis | Influenza A virus | 1 | organism-based format | Scientific Literature | ||
6. | ALA4845559 | F | Antiviral activity against Influenza A virus (A/WSN/1933(H1N1)) infected in MDCK cells assessed as inhibition of virus-induced cytopathic effect at 100 uM measured after 40 hrs incubation by inverted microscpic imaging analysis | Influenza A virus | 14 | organism-based format | Scientific Literature | ||
7. | ALA4845560 | B | Binding affinity to CM5 chip immobilized Influenza A virus (A/Michigan/45/2015) (H1N1)) hemagglutin assessed as dissociation constant by surface plasmon resonance assay | Influenza A virus | 1 | single protein format | Scientific Literature | ||
8. | ALA4845561 | F | Antiviral activity against Influenza A virus (A/Hong Kong/4801/2014 (H3N2)) infected in cells assessed as reduction in infected cells | Influenza A virus | 5 | organism-based format | Scientific Literature | ||
9. | ALA4845562 | F | Antiviral activity against Influenza B virus (B/Sichuan/531/2018(Victoria)) infected in cells assessed as reduction in infected cells | Influenza B virus | 5 | organism-based format | Scientific Literature | ||
10. | ALA4845563 | T | Selectivity index, ratio of CC50 for MDCK cells to IC50 for antiviral activity against Influenza A virus (A/Hong Kong/4801/2014 (H3N2)) | 4 | assay format | Scientific Literature | |||
11. | ALA4845564 | T | Selectivity index, ratio of CC50 for MDCK cells to IC50 for antiviral activity against Influenza A virus (B/Sichuan/531/2018(Victoria)) | 3 | assay format | Scientific Literature |