| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4816798 | F | Antiviral activity against HIV-1 infected in human CEM-SS cells assessed as reduction in viral multiplication by measuring decrease in reverse transcriptase activity incubated for 5 days | Human immunodeficiency virus 1 | 5 | ALA4813984 | organism-based format | Scientific Literature | |
| 2. | ALA4816799 | A | Cytotoxicity against human CEM-SS cells assessed as reduction in cell viability incubated for 5 days by MTT assay | Homo sapiens | 5 | ALA4813984 | cell-based format | Scientific Literature | |
| 3. | ALA4816800 | T | Selectivity index, ratio of CC50 for human CEM-SS cells to EC50 for antiviral activity against HIV-1 infected in human CEM-SS cells | 5 | ALA4813984 | cell-based format | Scientific Literature | ||
| 4. | ALA4816807 | F | Antiviral activity against HIV-1 infected in human MT4 cells assessed as reduction in virus-indued cytopathogenicity incubated for 5 days by MTT assay | Human immunodeficiency virus 1 | 5 | ALA4813984 | organism-based format | Scientific Literature | |
| 5. | ALA4816808 | A | Cytotoxicity against human MT4 cells assessed as reduction in cell viability incubated for 5 days by MTT assay | Homo sapiens | 5 | ALA4813984 | cell-based format | Scientific Literature | |
| 6. | ALA4816809 | T | Selectivity index, ratio of CC50 for human MT4 cells to EC50 for antiviral activity against HIV-1 infected in human MT4 cells | 5 | ALA4813984 | cell-based format | Scientific Literature | ||
| 7. | ALA4816816 | F | Antiviral activity against HIV-1 infected in human CEM-TK(-) cells assessed as reduction in viral multiplication by measuring decrease in reverse transcriptase activity incubated for 6 days | Human immunodeficiency virus 1 | 3 | ALA4813984 | organism-based format | Scientific Literature | |
| 8. | ALA4816817 | A | Cytotoxicity against human CEM-TK(-) cells assessed as reduction in cell viability incubated for 5 days by MTT assay | Homo sapiens | 3 | ALA4813984 | cell-based format | Scientific Literature | |
| 9. | ALA4816818 | T | Selectivity index, ratio of CC50 for human CEM-TK(-) cells to EC50 for antiviral activity against HIV-1 infected in human CEM-TK(-) cells | 2 | ALA4813984 | cell-based format | Scientific Literature | ||
| 10. | ALA4816822 | A | Stability of compound in human CEM-SS cell extract assessed as half life | Homo sapiens | 1 | ALA4813984 | tissue-based format | Scientific Literature | |
| 11. | ALA4816823 | P | Stability of compound in RPMI 1640 culture medium containing 10% heat-inactivated fetal calf serum assessed as half life | 1 | ALA4813984 | small-molecule physicochemical format | Scientific Literature |
The page will load shortly, Thanks for your patience!