# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA704873 | Functional | In vitro antiparasitic activity against Leishmania donovani was tested by sigmoidal regression analysis | Leishmania donovani | 59 | ALA1134791 | assay format | Scientific Literature | |
2. | ALA707388 | Binding | The second order rate constant of the TcLipDH (Trypanosoma cruzi lipoamide dehydrogenase) catalyzed NADH oxidation. | Trypanosoma cruzi | 6 | ALA1134791 | single protein format | Scientific Literature | |
3. | ALA859429 | Binding | The Michaelis-Menten constant for NADPH oxidation by TcLipDH (Trypanosoma cruzi lipoamide dehydrogenase) | Trypanosoma cruzi | 5 | ALA1134791 | single protein format | Scientific Literature | |
4. | ALA707389 | Binding | Vmax is the maximum velocity of the TcLipDH (Trypanosoma cruzi lipoamide dehydrogenase) catalyzed NADH oxidation | Trypanosoma cruzi | 6 | ALA1134791 | single protein format | Scientific Literature | |
5. | ALA879803 | Binding | Second order rate constant of the pig heart LipDH (lipoamide dehydrogenase) catalyzed NADH oxidation. | 2 | ALA1134791 | single protein format | Scientific Literature | ||
6. | ALA707391 | Binding | The Michaelis-Menten constant for NADPH oxidation by pig heart LipDH (lipoamide dehydrogenase) | 8 | ALA1134791 | single protein format | Scientific Literature | ||
7. | ALA707392 | Binding | Vmax is the maximum velocity of the pig heart LipDH (lipoamide dehydrogenase) catalyzed NADH oxidation | 8 | ALA1134791 | single protein format | Scientific Literature | ||
8. | ALA707394 | Binding | Ratio of cytochrome c reduction and NADH oxidation by pig heart LipDH (pig heart lipoamide dehydrogenase) at 50 uM concentration, cytochrome c assay | 1 | ALA1134791 | single protein format | Scientific Literature | ||
9. | ALA808704 | Functional | In vitro antiparasitic activity against Trypanosoma brucei was tested by sigmoidal regression analysis | Trypanosoma brucei | 75 | ALA1134791 | organism-based format | Scientific Literature | |
10. | ALA809368 | Functional | In vitro antiparasitic activity against Trypanosoma cruzi was tested by sigmoidal regression analysis | Trypanosoma cruzi | 62 | ALA1134791 | organism-based format | Scientific Literature | |
11. | ALA812445 | Binding | Ratio of cytochrome c reduction and NADH oxidation by TcLipDH (Trypanosoma cruzi lipoamide dehydrogenase) at 50 uM concentration, in cytochrome c assay | Trypanosoma cruzi | 6 | ALA1134791 | assay format | Scientific Literature | |
12. | ALA812446 | Binding | Inhibitory activity against Trypanosoma cruzi trypanothione disulfide reductase, assay in presence of 57 uM T(S)2. | Trypanosoma cruzi | 77 | ALA1134791 | single protein format | Scientific Literature | |
13. | ALA4480666 | Unassigned | Ratio of IC50 for cytotoxicity against rat RGC5 cells to IC50 for cytotoxicity against human HepG2 cells | 26 | ALA4480378 | cell-based format | Scientific Literature | ||
14. | ALA4480667 | Functional | Cytoprotection against rotenone-induced mitochondrial dysfunction in human HepG2 cells assessed as increase in cell viability by measuring ATP levels at 10 uM preincubated for 48 hrs followed by rotenone-induction and measured after 24 hrs by luciferase-based assay | Homo sapiens | 27 | ALA4480378 | cell-based format | Scientific Literature | |
15. | ALA4480670 | Functional | Cytoprotection against rotenone-induced mitochondrial dysfunction in human HepG2 cells assessed as acute ATP rescue at 10 uM co-treated with rotenone for 1 hr by luciferase-based assay relative to control | Homo sapiens | 34 | ALA4480378 | cell-based format | Scientific Literature | |
16. | ALA5053765 | Binding | Substrate activity at recombinant human NQO1 assessed as enzyme activity by measuring oxidation of NADPH incubated for 5 mins measured per micromol of NADPH by NADPH recycling assay | Homo sapiens | 5 | ALA5053491 | single protein format | Scientific Literature | |
17. | ALA5053766 | Binding | Substrate activity at recombinant human NQO1 assessed as ratio of Kcat to Km in presence of NADPH by Michaelis-Menten analysis | Homo sapiens | 5 | ALA5053491 | single protein format | Scientific Literature |