| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4815962 | F | Antitrypanosomal activity against Trypanosoma brucei brucei assessed as parasite growth inhibition | Trypanosoma brucei brucei | 40 | organism-based format | Scientific Literature | ||
| 2. | ALA4815964 | A | Cytotoxicity against mouse primary macrophage cells assessed as reduction in cell viability | Mus musculus | 39 | cell-based format | Scientific Literature | ||
| 3. | ALA4815965 | F | Antileishmanial activity against Leishmania infantum MHOM/MA(BE)/67 infected in mouse primary peritoneal macrophages treated 2 hrs post-infection and incubated for 5 days by Giemsa staining based microscopic analysis | Leishmania infantum | 40 | organism-based format | Scientific Literature | ||
| 4. | ALA4815966 | T | Selectivity index, ratio of EC50 for cytotoxicity against human MRC5 cells to EC50 for antitrypanosomal activity against Trypanosoma cruzi Tulahuen CL2 infected in human MRC5 cells | 26 | cell-based format | Scientific Literature | |||
| 5. | ALA4815967 | A | Cytotoxicity against human MRC5 cells assessed as reduction in cell viability after 3 days by resazurin dye based fluorimetric analysis | Homo sapiens | 39 | cell-based format | Scientific Literature | ||
| 6. | ALA4815968 | F | Antitrypanosomal activity against Trypanosoma cruzi Tulahuen CL2 infected in human MRC5 cells assessed as inhibition of parasite growth incubated for 7 days by chlorophenol red-fl-D-galactopyranoside based spectrophotometric analysis | Trypanosoma cruzi | 40 | organism-based format | Scientific Literature | ||
| 7. | ALA4815970 | F | Antitrypanosomal activity against Trypanosoma brucei rhodesiense assessed as parasite growth inhibition | Trypanosoma brucei rhodesiense | 40 | organism-based format | Scientific Literature | ||
| 8. | ALA4815971 | T | Selectivity index, ratio of EC50 for human MRC5 cells to EC50 for antitrypanosomal activity against Trypanosoma brucei brucei | 26 | assay format | Scientific Literature | |||
| 9. | ALA4815972 | T | Selectivity index, ratio of EC50 for human MRC5 cells to EC50 for antitrypanosomal activity against Trypanosoma brucei rhodesiense | 27 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!