# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4843199 | B | Agonist activity at human AMY3R (CT+RAMP3) expressed in Hollex1 cells incubated for 3 hrs by luminescence assay | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
2. | ALA4843200 | B | Agonist activity at human calcitonin receptor expressed in BHK570 cells assessed as increase in intracellular cAMP concentration incubated for 3 hrs in absence of albumin by CRE luciferase reporter gene assay | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
3. | ALA4843201 | B | Ratio of EC50 for human calcitonin receptor expressed in BHK570 cells to EC50 for human AMY3R (CT+RAMP3) expressed in Hollex1 cells | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
4. | ALA4843202 | B | Agonist activity at rat AMY3R (CT+RAMP3) expressed in tk-ts13 cells assessed as increase in intracellular cAMP level incuabted for 25 mins by CRE luciferase reporter gene assay | Rattus norvegicus | 29 | cell-based format | Scientific Literature | ||
5. | ALA4843203 | B | Agonist activity at rat calcitonin receptor expressed in BHK-13 cells assessed as increase in intracellular cAMP concentration incubated for 25 mins by CRE luciferase reporter gene assay | Rattus norvegicus | 29 | cell-based format | Scientific Literature | ||
6. | ALA4843211 | P | Solubility of the compound in lactate at pH 3 by UPLC analysis | 27 | small-molecule physicochemical format | Scientific Literature | |||
7. | ALA4843212 | P | Solubility of the compound in lactate at pH 4 by UPLC analysis | 27 | small-molecule physicochemical format | Scientific Literature | |||
8. | ALA4843213 | P | Solubility of the compound in lactate at pH 5 by UPLC analysis | 27 | small-molecule physicochemical format | Scientific Literature | |||
9. | ALA4843214 | P | Solubility of the compound in bis-tris propane at pH 6 by UPLC analysis | 27 | small-molecule physicochemical format | Scientific Literature | |||
10. | ALA4843215 | P | Solubility of the compound in bis-tris propane at pH 6.5 by UPLC analysis | 27 | small-molecule physicochemical format | Scientific Literature | |||
11. | ALA4843216 | P | Solubility of the compound in bis-tris propane at pH 7 by UPLC analysis | 27 | small-molecule physicochemical format | Scientific Literature | |||
12. | ALA4843217 | P | Solubility of the compound in bis-tris propane at pH 7.5 by UPLC analysis | 27 | small-molecule physicochemical format | Scientific Literature | |||
13. | ALA4843218 | P | Solubility of the compound in bis-tris propane at pH 8 by UPLC analysis | 27 | small-molecule physicochemical format | Scientific Literature | |||
14. | ALA4843219 | B | Effect on insulin (unknown origin) amyloid fibril formation assessed as lag time in glycyl-glycine buffer at pH 4 measured after 45 hrs by thioflavin-T fluorescence assay | Homo sapiens | 27 | single protein format | Scientific Literature | ||
15. | ALA4843220 | B | Effect on insulin (unknown origin) amyloid fibril formation assessed as peptide recovery in glycyl-glycine buffer at pH 4 measured after 45 hrs by thioflavin-T fluorescence assay relative to control | Homo sapiens | 27 | single protein format | Scientific Literature | ||
16. | ALA4843221 | B | Effect on insulin (unknown origin) amyloid fibril formation assessed as lag time in HEPES buffer at pH 7.5 measured after 45 hrs by thioflavin-T fluorescence assay | Homo sapiens | 27 | single protein format | Scientific Literature | ||
17. | ALA4843222 | B | Effect on insulin (unknown origin) amyloid fibril formation assessed as peptide recovery in HEPES buffer at pH 7.5 measured after 45 hrs by thioflavin-T fluorescence assay relative to control | Homo sapiens | 27 | single protein format | Scientific Literature | ||
18. | ALA4843223 | F | Reduction in food intake in Sprague-Dawley rat at 30 nmol/kg, sc administered as single dose measured upto 24 hrs relative to control | Rattus norvegicus | 27 | organism-based format | Scientific Literature | ||
19. | ALA4843224 | F | Reduction in food intake in Sprague-Dawley rat at 30 nmol/kg, sc administered as single dose measured after 24 to 48 hrs relative to control | Rattus norvegicus | 27 | organism-based format | Scientific Literature | ||
20. | ALA4843225 | F | Reduction in food intake in Sprague-Dawley rat at 3 nmol/kg, sc administered as single dose measured upto 24 hrs relative to control | Rattus norvegicus | 27 | organism-based format | Scientific Literature |