#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4834988	B	Inhibition of recombinant SAE (unknown origin) assessed as reduction in transfer of SUMO1 to UBC9 using SUMO1 as a substrate in presence of ATP at Km concentration by HTRF assay	Homo sapiens	60		protein complex format	Scientific Literature
2.	ALA4834989	B	Inhibition of recombinant UAE (unknown origin) in presence of ATP at Km concentration by HTRF assay	Homo sapiens	60		assay format	Scientific Literature
3.	ALA4834990	B	Inhibition of recombinant NAE (unknown origin) in presence of ATP at Km concentration by HTRF assay	Homo sapiens	60		protein complex format	Scientific Literature
4.	ALA4834998	B	Inhibition of SAE in human HCT116 cells assessed as reduction in redistribution of SUMO2/3 proteins from nucleus to cytosol incubated for 4 hrs by immunofluorescence assay	Homo sapiens	59		cell-based format	Scientific Literature
5.	ALA4835005	B	Inhibition of SAE in human HCT116 cells xenografted in NCr nude mouse assessed as reduction in SUMO2/3 protein conjugates at 50 mg/kg, iv and measured up to 16 hrs by immunohistochemistry analysis	Homo sapiens	2		organism-based format	Scientific Literature
6.	ALA4835007	B	Inhibition of SAE in human HCT116 cells xenografted in NCr nude mouse assessed as improvement in SUMO-inhibitor adduct durability at 50 mg/kg, iv and measured up to 16 hrs by mass spectrometry	Homo sapiens	2		organism-based format	Scientific Literature
7.	ALA4835009	F	Cytotoxicity against human HCT116 cells assessed as reduction in cell viability after 72 hrs by CellTiter-Glo luminescent assay	Homo sapiens	3		cell-based format	Scientific Literature
8.	ALA4835010	F	Cytotoxicity against human OCI-LY10 cells assessed as reduction in cell viability after 72 hrs by CellTiter-Glo luminescent assay	Homo sapiens	3		cell-based format	Scientific Literature
9.	ALA4835011	F	Antitumor activity against human HCT-116 cells xenografted in Ncr/nude mouse assessed as tumor growth inhibition at 50 mg/kg, sc administered once daily for 21 days and measured twice weekly	Homo sapiens	1		organism-based format	Scientific Literature
10.	ALA4835013	F	Antitumor activity against human OCI-Ly10 cells xenografted in CB17 SCID mouse assessed as tumor growth inhibition at 50 mg/kg, sc mg/kg administered once daily for 21 days and measured twice weekly	Homo sapiens	1		organism-based format	Scientific Literature
11.	ALA4835015	P	Lipophilicity, logD of compound at pH 7.4		3		small-molecule physicochemical format	Scientific Literature
12.	ALA4835016	P	Dissociation constant , pKa of the compound		3		small-molecule physicochemical format	Scientific Literature
13.	ALA4835017	A	Apparent permeability across apical to basolateral side in human Caco2 cells	Homo sapiens	3		cell-based format	Scientific Literature
14.	ALA4835018	A	Apparent permeability across basolateral to apical side in human Caco2 cells	Homo sapiens	3		cell-based format	Scientific Literature
15.	ALA4835019	A	Efflux ratio of apparent permeability across basolateral to apical side over apical to basolateral side in human Caco-2 cells	Homo sapiens	3		cell-based format	Scientific Literature
16.	ALA4835020	P	Solubility of compound in 10% hydroxypropyl-beta-cyclodextrin after 24 hrs		2		small-molecule physicochemical format	Scientific Literature
17.	ALA4835021	B	Inhibition of human erythrocyte CA1 using fluorescein diacetate as substrate at pH 3.5 by fluorometric esterase assay	Homo sapiens	3		single protein format	Scientific Literature
18.	ALA4835022	B	Inhibition of recombinant human CA2 expressed in Escherichia coli using fluorescein diacetate as substrate at pH 3.5 by fluorometric esterase assay	Homo sapiens	3		assay format	Scientific Literature
19.	ALA4835023	A	AUC in rat blood at 1 mg/kg, iv	Rattus norvegicus	3		organism-based format	Scientific Literature
20.	ALA4835024	A	AUC in rat plasma at 1 mg/kg, iv	Rattus norvegicus	3		organism-based format	Scientific Literature