| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4834035 | Binding | Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay | Homo sapiens | 50 | ALA4831554 | cell-based format | Scientific Literature | |
| 2. | ALA4834036 | Physicochemical | Lipophilicity, logD of the compound in Octanol/phosphate buffer at pH 7.4 after 30 mins by shake-flask method | 50 | ALA4831554 | small-molecule physicochemical format | Scientific Literature | ||
| 3. | ALA4834037 | ADME | Intrinsic clearance in human liver microsomes at 1 uM preincubated with NADPH for 5 mins followed by compound addition and measured upto 30 mins by LC-MS/MS analysis | Homo sapiens | 50 | ALA4831554 | microsome format | Scientific Literature | |
| 4. | ALA4834038 | Physicochemical | Solubility of compound in phosphate buffer at pH 7.4 measured after 24 hrs by LC-MS/MS analysis | 50 | ALA4831554 | small-molecule physicochemical format | Scientific Literature | ||
| 5. | ALA4834039 | Functional | Antiproliferative activity against human KARPAS-422 cells assessed as growth inhibition after 14 days by CellTiter-Glo luminescent cell viability assay | Homo sapiens | 8 | ALA4831554 | cell-based format | Scientific Literature | |
| 6. | ALA4834040 | ADME | Clearance in rat at 1 mg/kg, po or 0.5 mg/kg, iv | Rattus norvegicus | 9 | ALA4831554 | organism-based format | Scientific Literature | |
| 7. | ALA4834041 | ADME | Volume of distribution at steady state in rat at 1 mg/kg, po or 0.5 mg/kg, iv | Rattus norvegicus | 9 | ALA4831554 | organism-based format | Scientific Literature | |
| 8. | ALA4834042 | ADME | Bioavailability in rat at 1 mg/kg, po or 0.5 mg/kg, iv | Rattus norvegicus | 8 | ALA4831554 | organism-based format | Scientific Literature | |
| 9. | ALA4834043 | ADME | Intrinsic clearance in human hepatocytes assessed per million cells at 1 uM measured upto 30 mins by HPLC analysis | Homo sapiens | 8 | ALA4831554 | cell-based format | Scientific Literature | |
| 10. | ALA4834044 | Physicochemical | Thermodynamic solubility in phosphate buffer at pH 6.9 after 24 hrs by LC/UV analysis | 8 | ALA4831554 | small-molecule physicochemical format | Scientific Literature |
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