# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4827270 | B | Inhibition of human carbonic anhydrase 1 assessed as inhibition constant incubated for 15 mins prior to testing by phenol red based stopped-flow CO2 hydration assay | Homo sapiens | 18 | single protein format | Scientific Literature | ||
2. | ALA4827271 | B | Inhibition of human carbonic anhydrase 2 assessed as inhibition constant incubated for 15 mins prior to testing by phenol red based stopped-flow CO2 hydration assay | Homo sapiens | 18 | single protein format | Scientific Literature | ||
3. | ALA4827272 | B | Inhibition of human carbonic anhydrase 9 assessed as inhibition constant incubated for 15 mins prior to testing by phenol red based stopped-flow CO2 hydration assay | Homo sapiens | 18 | single protein format | Scientific Literature | ||
4. | ALA4827273 | B | Inhibition of human carbonic anhydrase 12 assessed as inhibition constant incubated for 15 mins prior to testing by phenol red based stopped-flow CO2 hydration assay | Homo sapiens | 18 | single protein format | Scientific Literature | ||
5. | ALA4827274 | F | Antiproliferative activity against human U-87 MG cells assessed as cell growth inhibition at 30 to 100 uM measured after 24 hrs under CoCl2-induced hypoxic condition by MTT assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
6. | ALA4827275 | F | Antiproliferative activity against human U-87 MG cells assessed as cell survival rate at 300 uM measured after 24 hrs under CoCl2-induced hypoxic condition by MTT assay relative to control | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
7. | ALA4827278 | F | Antiproliferative activity against human A-431 cells assessed as cell survival rate at 100 uM measured after 24 hrs under CoCl2-induced hypoxic condition by MTT assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
8. | ALA4827279 | F | Antiproliferative activity against human A-431 cells assessed as cell survival rate at 300 uM measured after 24 hrs under CoCl2-induced hypoxic condition by MTT assay relative to control | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
9. | ALA4827281 | F | Antiproliferative activity against human A-431 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
10. | ALA4827282 | F | Antiproliferative activity against human A-431 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
11. | ALA4827283 | F | Antiproliferative activity against human A-431 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
12. | ALA4827284 | F | Antiproliferative activity against human WI-26 AV4 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
13. | ALA4827285 | F | Antiproliferative activity against human WI-26 AV4 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
14. | ALA4827286 | F | Antiproliferative activity against human WI-26 AV4 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
15. | ALA4827287 | F | Induction of apoptosis in human A-431 cells assessed as viable cells at 5 uM incubated for 24 hrs by annexin-V/FITC and propidium iodide based staining based flow cytometry (Rvb= 90.70 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
16. | ALA4827288 | F | Induction of apoptosis in human A-431 cells assessed as early apoptotic cells at 5 uM incubated for 24 hrs by annexin-V/FITC and propidium iodide based staining based flow cytometry (Rvb= 6.10 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
17. | ALA4827289 | F | Induction of apoptosis in human A-431 cells assessed as late apoptotic cells at 5 uM incubated for 24 hrs by annexin-V/FITC and propidium iodide based staining based flow cytometry (Rvb= 3.06 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
18. | ALA4827290 | F | Induction of apoptosis in human A-431 cells assessed as dead cells at 5 uM incubated for 24 hrs by annexin-V/FITC and propidium iodide based staining based flow cytometry (Rvb= 0.14 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
19. | ALA4827291 | F | Induction of apoptosis in human A-431 cells assessed as viable cells at 10 uM incubated for 24 hrs by annexin-V/FITC and propidium iodide based staining based flow cytometry (Rvb= 90.70 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
20. | ALA4827292 | F | Induction of apoptosis in human A-431 cells assessed as early apoptotic cells at 10 uM incubated for 24 hrs by annexin-V/FITC and propidium iodide based staining based flow cytometry (Rvb= 6.10 %) | Homo sapiens | 1 | cell-based format | Scientific Literature |