# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4828160 | B | Inhibition of FLAG-tagged MER (unknown origin) transfected in Cos-7cells assessed as phosphorylation level incubated for 1 hr by ELISA | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
2. | ALA4828161 | B | Inhibition of FLAG-tagged AXL (unknown origin) transfected in Cos-7 cells assessed as phosphorylation level incubated for 1 hr by ELISA | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
3. | ALA4828162 | B | Inhibition of FLAG-tagged FLT3 (unknown origin) transfected in Cos-7 cells assessed as phosphorylation level incubated for 1 hr by ELISA | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
4. | ALA4828163 | P | Lipophilicity, log D of the compound at pH 7.4 | 35 | small-molecule physicochemical format | Scientific Literature | |||
5. | ALA4828164 | B | Inhibition of FLAG-tagged Tyro3 (unknown origin) transfected in Cos-7 cells assessed as phosphorylation level incubated for 1 hr by ELISA | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
6. | ALA4828166 | F | Induction efferocytosis in human PBMC assessed as CD14-positive monocytes | Homo sapiens | 12 | tissue-based format | Scientific Literature | ||
7. | ALA4828167 | F | Growth inhibition of mouse BaF3 cells transfected with MER assessed as inhibition of cell growth incubated for 72 hrs by Cell-titer-Glo assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
8. | ALA4828168 | F | Growth inhibition of mouse BaF3 cells transfected with AXL assessed as inhibition of cell growth incubated for 72 hrs by Cell-titer-Glo assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
9. | ALA4828169 | F | Growth inhibition of mouse BaF3 cells transfected with FLT3 assessed as inhibition of cell growth incubated for 72 hrs by Cell-titer-Glo assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
10. | ALA4828170 | F | Growth inhibition of mouse BaF3 cells transfected with Tyro3 assessed as inhibition of cell growth incubated for 72 hrs by Cell-titer-Glo assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
11. | ALA4828171 | F | Growth inhibition of mouse BaF3 cells assessed as inhibition of cell growth incubated for 72 hrs by Cell-titer-Glo assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
12. | ALA4828174 | F | Antitumour activity against mouse BaF3 cells transfected with MER implanted in C57BL/6J mouse assessed as reduction in tumour growth at 3 to 100 mg/kg, po bid for 6 days | Mus musculus | 1 | organism-based format | Scientific Literature | ||
13. | ALA4828176 | F | Antitumour activity against mouse BaF3 cells transfected with AXL implanted in C57BL/6J mouse assessed as reduction in tumour growth at 100 mg/kg, po bid for 6 days | Mus musculus | 1 | organism-based format | Scientific Literature | ||
14. | ALA4828177 | A | Fraction unbound in C57BL/6J mouse implanted with mouse BaF3 cells transfected with MER in at 3 to 100 mg/kg, po bid for 6 days | Mus musculus | 2 | organism-based format | Scientific Literature | ||
15. | ALA4828178 | A | Fraction unbound in C57BL/6J mouse implanted with mouse BaF3 cells transfected with AXL in at 3 to 100 mg/kg, po bid for 6 days | Mus musculus | 2 | organism-based format | Scientific Literature | ||
16. | ALA4828179 | F | Antitumour activity against mouse BaF3 cells transfected with MER implanted in C57BL/6J mouse assessed as reduction in MER phosphorylation at 30 to 100 mg/kg, po bid for 6 days by western blot analysis | Mus musculus | 2 | organism-based format | Scientific Literature | ||
17. | ALA4828180 | F | Antitumour activity against mouse BaF3 cells transfected with AXL implanted in C57BL/6J mouse assessed as reduction in AXL phosphorylation at 30 to 100 mg/kg, po bid for 6 days western blot analysis | Mus musculus | 2 | organism-based format | Scientific Literature | ||
18. | ALA4828181 | F | Antitumour activity against mouse MC38 cells implanted in C57BL6 mouse assessed as increase in survival at 100 mg/kg, po bid for 2 weeks co-treatment with anti-PD1 further treated with ionizing radiation | Mus musculus | 2 | organism-based format | Scientific Literature |