# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4835313 | Binding | Inhibition of recombinant human activated TAFI incubated for 45 mins using hippuryl-arginine as substrate by spectrophotometry | Homo sapiens | 55 | ALA4834413 | single protein format | Scientific Literature | |
2. | ALA4835333 | Binding | Inhibition of TAFI in Sprague-Dawley rat blood TAFI at 0.8 uM incubated for 2 mins using hippuryl-arginine as substrate by thromboelastometry analysis relative to control | Rattus norvegicus | 14 | ALA4834413 | tissue-based format | Scientific Literature | |
3. | ALA4835334 | Binding | Inhibition of TAFI in Sprague-Dawley rat blood TAFI incubated for 2 mins using hippuryl-arginine as substrate by thromboelastometry analysis | Rattus norvegicus | 2 | ALA4834413 | tissue-based format | Scientific Literature | |
4. | ALA4835335 | Functional | Ex vivo inhibition of TAFI in Sprague-Dawley rat blood TAFI at 0.6 mg/kg, iv measured after 30 mins by thromboelastometry analysis relative to control | Rattus norvegicus | 11 | ALA4834413 | organism-based format | Scientific Literature | |
5. | ALA4835336 | Functional | Ex vivo inhibition of TAFI in Sprague-Dawley rat blood TAFI at 0.6 mg/kg, iv measured after 60 mins by thromboelastometry analysis relative to control | Rattus norvegicus | 13 | ALA4834413 | organism-based format | Scientific Literature |