# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4818879 | ADME | Inhibition of CYP2C19 (unknown origin) at 20 uM | Homo sapiens | 4 | ALA4814074 | single protein format | Scientific Literature | |
2. | ALA4818880 | ADME | Inhibition of CYP2D6 (unknown origin) at 20 uM | Homo sapiens | 4 | ALA4814074 | single protein format | Scientific Literature | |
3. | ALA4818881 | ADME | Inhibition of CYP2B6 (unknown origin) at 20 uM | Homo sapiens | 4 | ALA4814074 | single protein format | Scientific Literature | |
4. | ALA4818882 | ADME | Inhibition of CYP2C9 (unknown origin) at 20 uM | Homo sapiens | 4 | ALA4814074 | single protein format | Scientific Literature | |
5. | ALA4818884 | ADME | Inhibition of CYP3A4 (unknown origin) at 20 uM | Homo sapiens | 4 | ALA4814074 | single protein format | Scientific Literature | |
6. | ALA4818885 | ADME | Inhibition of CYP1A2 (unknown origin) at 20 uM | Homo sapiens | 4 | ALA4814074 | single protein format | Scientific Literature | |
7. | ALA4818886 | Functional | Antiviral activity against Lassa virus by virus yield reduction assay | Mammarenavirus lassaense | 4 | ALA4814074 | organism-based format | Scientific Literature | |
8. | ALA4818887 | Toxicity | Selectivity index, ratio of CC50 for African green monkey Vero cells to EC90 for Lassa virus by virus yield reduction assay | 4 | ALA4814074 | assay format | Scientific Literature | ||
9. | ALA4818889 | Functional | Antiviral activity against Lassa virus by plaque reduction assay | Mammarenavirus lassaense | 4 | ALA4814074 | organism-based format | Scientific Literature | |
10. | ALA4818890 | Toxicity | Selectivity index, ratio of CC50 for African green monkey Vero cells to EC90 for Lassa virus by plaque reduction assay | 4 | ALA4814074 | assay format | Scientific Literature | ||
11. | ALA4818891 | Functional | Antiviral activity against pseudotyped Lassa mammarenavirus | Mammarenavirus lassaense | 49 | ALA4814074 | organism-based format | Scientific Literature | |
12. | ALA4818892 | Functional | Antiviral activity against pseudotyped Machupo virus | Mammarenavirus machupoense | 49 | ALA4814074 | organism-based format | Scientific Literature | |
13. | ALA4818893 | Functional | Antiviral activity against pseudotyped Junin virus | Mammarenavirus juninense | 49 | ALA4814074 | organism-based format | Scientific Literature | |
14. | ALA4818895 | ADME | Cytotoxicity against African green monkey Vero cells measured after 5 days | Chlorocebus sabaeus | 21 | ALA4814074 | cell-based format | Scientific Literature | |
15. | ALA4818897 | Binding | Inhibition of human ERG at 3 uM relative to control | Homo sapiens | 12 | ALA4814074 | single protein format | Scientific Literature | |
16. | ALA4818898 | ADME | Metabolic stability in human liver microsomes assessed as parent compound remaining measured after 60 mins | Homo sapiens | 13 | ALA4814074 | microsome format | Scientific Literature | |
17. | ALA4818899 | ADME | Metabolic stability in guinea pig liver microsomes assessed as parent compound remaining measured after 60 mins | Cavia porcellus | 13 | ALA4814074 | microsome format | Scientific Literature | |
18. | ALA4818900 | ADME | Metabolic stability in mouse liver microsomes assessed as parent compound remaining measured after 60 mins | Mus musculus | 11 | ALA4814074 | microsome format | Scientific Literature | |
19. | ALA4818901 | ADME | Metabolic stability in cynomolgus monkey liver microsomes assessed as parent compound remaining measured after 60 mins | Macaca fascicularis | 12 | ALA4814074 | microsome format | Scientific Literature | |
20. | ALA4818902 | ADME | Metabolic stability in dog liver microsomes assessed as parent compound remaining measured after 60 mins | Canis lupus familiaris | 8 | ALA4814074 | microsome format | Scientific Literature |