# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4827795 | Binding | Displacement of fluorophore-labeled RIOK1 from human PRMT5/WDR77 hetero octameric complex expressed in Sf9 cells by competition fluorescence polarization (FP) assay | Homo sapiens | 33 | ALA4825730 | cell-based format | Scientific Literature | |
2. | ALA4827796 | Physicochemical | Solubility in PBS buffer | 33 | ALA4825730 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA4827797 | ADME | Stability in human plasma assessed as compound remaining relative to control | Homo sapiens | 33 | ALA4825730 | cell-free format | Scientific Literature | |
4. | ALA4827798 | ADME | Stability in mouse plasma assessed as compound remaining relative to control | Mus musculus | 33 | ALA4825730 | cell-free format | Scientific Literature | |
5. | ALA4827799 | Physicochemical | Glutathione reactivity assessed as stability by measuring glutathione half life at 10 uM measured up to 1440 mins by LC-MS/MS analysis | 12 | ALA4825730 | small-molecule physicochemical format | Scientific Literature |