# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4815607 | Binding | Selectivity index, ratio of pKi for displacement of [3H]NMS from human recombinant muscarinic receptor M3 expressed in CHO cell membranes to pKi for displacement of [3H]NMS from human recombinant muscarinic receptor M2 expressed in CHO cell membranes | Homo sapiens | 30 | ALA4813954 | cell-based format | Scientific Literature | |
2. | ALA4815608 | Binding | Selectivity index, ratio of pKi for displacement of [3H]NMS from human recombinant muscarinic receptor M1 expressed in CHO cell membranes to pKi for displacement of [3H]NMS from human recombinant muscarinic receptor M2 expressed in CHO cell membranes | Homo sapiens | 76 | ALA4813954 | cell-based format | Scientific Literature | |
3. | ALA4815609 | Binding | Displacement of [3H]-NMS from human muscarinic M1 receptor expressed in CHO cell membranes assessed as inhibition constant by radioligand competition analysis | Homo sapiens | 76 | ALA4813954 | cell membrane format | Scientific Literature | |
4. | ALA4815610 | Binding | Displacement of [3H]-NMS from human muscarinic M2 receptor expressed in CHO cell membranes assessed as inhibition constant by radioligand competition analysis | Homo sapiens | 79 | ALA4813954 | cell membrane format | Scientific Literature | |
5. | ALA4815611 | Binding | Displacement of [3H]-NMS from human muscarinic M3 receptor expressed in CHO cell membranes assessed as inhibition constant by radioligand competition analysis | Homo sapiens | 30 | ALA4813954 | cell membrane format | Scientific Literature | |
6. | ALA4815612 | Binding | Displacement of [3H]-NMS from human muscarinic M4 receptor expressed in CHO cell membranes assessed as inhibition constant by radioligand competition analysis | Homo sapiens | 76 | ALA4813954 | cell membrane format | Scientific Literature | |
7. | ALA4815613 | Binding | Displacement of [3H]-NMS from human muscarinic M5 receptor expressed in CHO cell membranes assessed as inhibition constant by radioligand competition analysis | Homo sapiens | 29 | ALA4813954 | cell membrane format | Scientific Literature | |
8. | ALA4815614 | Binding | Selectivity index, ratio of pKi for displacement of [3H]NMS from human recombinant muscarinic receptor M4 expressed in CHO cell membranes to pKi for displacement of [3H]NMS from human recombinant muscarinic receptor M2 expressed in CHO cell membranes | Homo sapiens | 76 | ALA4813954 | cell-based format | Scientific Literature | |
9. | ALA4815615 | Binding | Selectivity index, ratio of pKi for displacement of [3H]NMS from human recombinant muscarinic receptor M5 expressed in CHO cell membranes to pKi for displacement of [3H]NMS from human recombinant muscarinic receptor M2 expressed in CHO cell membranes | Homo sapiens | 29 | ALA4813954 | cell-based format | Scientific Literature | |
10. | ALA4815616 | Functional | Antagonist activity at human muscarinic acetylcholine receptor M2 expressed in human HEK293T cells coexpressing NlucN-mini-Gsi assessed as inhibition of iperoxo-induced mini-Gsi recruitment by measuring equilibrium binding constant by nano-luciferase technique | Homo sapiens | 3 | ALA4813954 | cell-based format | Scientific Literature |