# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4821931 | Functional | Prevention of doxorubicin-induced Zebrafish mortality assessed as survival rate at 40 uM incubated for 48 hrs by inverted fluorescence microscopy (Rvb = 52%) | Danio rerio | 26 | ALA4819088 | organism-based format | Scientific Literature | |
2. | ALA4821932 | Functional | Prevention of doxorubicin-induced Zebrafish mortality assessed as increase in survival rate incubated for 48 hrs by inverted fluorescence microscopy | Danio rerio | 6 | ALA4819088 | organism-based format | Scientific Literature | |
3. | ALA4821933 | Functional | Cardioprotective activity in (cmlc2:GFP) transgenic Zebrafish assessed as reduction in doxorubicin-induced cardiac edema measured after 48 hrs | Danio rerio | 6 | ALA4819088 | organism-based format | Scientific Literature | |
4. | ALA4821934 | Functional | Cardioprotective activity in (cmlc2:GFP) transgenic Zebrafish assessed as prevention of doxorubicin-induced heart shape change measured after 48 hrs | Danio rerio | 6 | ALA4819088 | organism-based format | Scientific Literature | |
5. | ALA4821935 | Functional | Cardioprotective activity in (cmlc2:GFP) transgenic Zebrafish assessed as reduction in doxorubicin-induced cardiac impairment measured after 48 hrs | Danio rerio | 6 | ALA4819088 | organism-based format | Scientific Literature | |
6. | ALA4821936 | Functional | Cardioprotective activity against doxorubicin-induced (cmlc2:GFP) transgenic Zebrafish assessed as protection of heart measured after 48 hrs | Danio rerio | 6 | ALA4819088 | organism-based format | Scientific Literature | |
7. | ALA4821937 | Functional | Cardioprotective activity against doxorubicin-induced (cmlc2:GFP) transgenic Zebrafish assessed as protection of heart function loss measured after 48 hrs | Danio rerio | 6 | ALA4819088 | organism-based format | Scientific Literature | |
8. | ALA4821938 | Functional | Cardioprotective activity against Zebrafish assessed as reduction in doxorubicin-induced increase in Cardiac troponin T mRNA level by qRT-PCR analysis | Danio rerio | 1 | ALA4819088 | organism-based format | Scientific Literature | |
9. | ALA4821939 | Functional | Cardioprotective activity against Zebrafish assessed as reduction in doxorubicin-induced increase in natriuretic peptide mRNA level by qRT-PCR analysis | Danio rerio | 1 | ALA4819088 | organism-based format | Scientific Literature | |
10. | ALA4821940 | Functional | Cardioprotective activity against doxorubicin-induced rat H9c2 cells assessed as protection of cell damage measured after 48 hrs by CCK8 assay | Rattus norvegicus | 1 | ALA4819088 | cell-based format | Scientific Literature | |
11. | ALA4821941 | Functional | Cardioprotective activity against rat H9c2 cells assessed as inhibition of doxorubicin-induced ROS production preincubated for 48 hrs followed by loading with DCFDA dye for 40 mins by DCF-DA probe based fluorescence assay | Rattus norvegicus | 1 | ALA4819088 | cell-based format | Scientific Literature | |
12. | ALA4821942 | Functional | Cardioprotective activity against rat H9c2 cells assessed as inhibition of doxorubicin-induced mitochondrial membrane potential loss incubated for 48 hrs by JC1 staining based flow cytometry | Rattus norvegicus | 1 | ALA4819088 | cell-based format | Scientific Literature |